Abstract： Objective： To observe the clinical effect of Weifuchun Capsules in adjuvant treatment of chronic superficial gastritis (CSG) with spleen- stomach weakness syndrome and its effect on the level of serum gastrin (GAS). Methods：A total of 128 cases with CSG with spleen-stomach weakness syndrome were retrospectively studied and divided into the control group and the observation group according to different treatment methods，with 64 cases in each group. The control group was treated with Omeprazole Enteric- soluble Capsules orally， and the observation group was additionally given Weifuchun Capsules based on the treatment of the control group. The clinical effects，positive rates of helicobacter pylori (Hp)， the incidence of adverse reactions，traditional Chinese medicine syndrome scores as well as the levels of serum GAS in the two groups were compared. Results： The total effective rate was 93.75% in the observation group，higher than that of 81.25% in the control group，the difference being significant (P＜ 0.05). Before treatment， there was no significant difference being found in the comparisons of TCM syndrome scores of stuffiness and stagnation in the stomach duct， dull pain， torpid intake and poor appetite， abdominal distension and oppression after eating， lack of strength in limbs between the two groups (P＞0.05)； after treatment， the five scores above in the two groups were decreased when compared with those before treatment (P＜0.05)，and the five scores in the observation group were lower than those in the control group (P＜0.05). Before treatment，there was no significant difference being found in the comparison of Hp positive rates between the two groups (P＞0.05)；after treatment，the Hp positive rates in both groups were decreased when compared with those before treatment (P＜0.05)，and the Hp positive rate in the observation group was lower than that in the control group (P＜0.05). Before treatment， there was no significant difference being found when comparing the levels of serum GSA between the two groups (P＞0.05)； after treatment， the levels of serum GSA in both groups were increased when compared with those before treatment (P＜0.05)，and the level of serum GSA in the observation group was higher than that in the control group (P＜0.05). The incidence of adverse reactions was 7.81% in the observation group， lower than that of 18.75% in the control group， the difference being significant (P＜ 0.05). Conclusion：Weifuchun Capsules in adjuvant treatment of western medicine for CSG with spleenstomach weakness syndrome can increase the clinical effect，improve the level of serum GSA and the TCM syndrome，and decrease the Hp positive rate and the incidence of adverse reactions.