烧山火针法联合酪酸梭菌活菌胶囊治疗慢性腹泻寒湿证临床研究
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R256.34;R246.1

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Clinical Study on Shaoshanhuo Needling Method Combined with Clostridum Butyricum Capsules for Chronic Diarrhea with Cold-Damp Syndrome
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    摘要:

    目的:观察烧山火针法联合酪酸梭菌活菌胶囊治疗慢性腹泻寒湿证的临床疗效。方法:选取98 例 慢性腹泻寒湿证患者,按随机数字表法分为对照组和观察组,每组49 例。对照组予以酪酸梭菌活菌胶囊治 疗,观察组在对照组基础上予以烧山火针法治疗,2 组均治疗4 周。比较2 组临床疗效,治疗前后大便次数、 大便性状评分、营养学指标[血红蛋白(Hb)、白蛋白(Alb)、总蛋白(TP)] 水平,以及治疗期间的不良反 应发生率。结果:治疗后,观察组临床疗效总有效率91.84%,高于对照组75.51% (P<0.05)。治疗后, 2 组大便次数均较治疗前减少(P<0.05),Bristol 粪便性状评估表(BSFS) 评分均较治疗前降低(P<0.05); 观察组大便次数少于对照组(P<0.05),BSFS 评分低于对照组(P<0.05)。治疗后,2 组血清Hb、Alb、TP 水平均较治疗前升高(P<0.05),观察组血清Hb、Alb、TP 水平均高于对照组(P<0.05)。治疗期间,观察组 不良反应发生率8.16%,与对照组4.08%比较,差异无统计学意义(P>0.05)。结论:烧山火针法联合酪酸梭 菌活菌胶囊治疗慢性腹泻寒湿证效果确切,可促进症状缓解,改善患者的营养状况,安全性良好。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Shaoshanhuo needling method combined with Clostridum Butyricum Capsules on chronic diarrhea with cold-damp syndrome. Methods:A total of 98 patients with chronic diarrhea with cold- damp syndrome were selected and divided into the control group and the observation group according to the random number table method,with 49 cases in each group. The control group was treated with Clostridum Butyricum Capsules,and the observation group was additionally given Shaoshanhuo needling method based on the treatment of the control group. Both groups were treated for 4 weeks. The clinical effects, and the defection times, the scores of stool form and levels of nutritional indexes including hemoglobin (Hb),albumin (Alb) and total protein (TP) before and after treatment as well as the incidence of adverse reactions during treatment were compared between the two groups. Results: After treatment,the total clinical effective rate was 91.84% in the observation group,higher than that of 75.51% in the control group (P<0.05). After treatment,the defecation times in both groups were reduced when compared with those before treatment (P<0.05),and the scores of Bristol Stool Form Scale (BSFS) were decreased when compared with those before treatment (P<0.05); the defecation time in the observation group was less than that in the control group (P<0.05),and the BSFS score was lower than that in the control group (P<0.05). After treatment,the levels of serum Hb,Alb and TP in the two groups were increased when compared with those before treatment (P<0.05), and the above 3 levels in the observation group were higher than those in the control group (P<0.05). During treatment,the incidence of adverse reactions was 8.16% in the observation group and 4.08% in the control group, there being no significance in the difference (P>0.05). Conclusion: Shaoshanhuo needling method combined with Clostridum Butyricum Capsules has a definite effect on chronic diarrhea with cold-damp syndrome,which can promote the mitigation of symptoms and improve the nutritional status of patients,with good safety.

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朱苏生,虞美华.烧山火针法联合酪酸梭菌活菌胶囊治疗慢性腹泻寒湿证临床研究[J].新中医,2023,55(6):140-144

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  • 在线发布日期: 2023-03-28
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