Abstract： Objective： To observe the clinical effect of extracorporeal shock wave combined with internal heat acupuncture for lower back myofasciitis. Methods：A total of 106 cases of patients with lower back myofasciitis were selected and divided into the control group and the combination group according to the random number table method，with 53 cases in each group. The control group was treated with internal heat acupuncture，and the combination group was treated with extracorporeal shock wave combined with internal heat acupuncture. Both groups were continuously treated for 4 consecutive weeks. Clinical effects were evaluated in the two groups. Oswestry Dysfunction Index (ODI)， substance P and tumor necrosis factor-α (TNF-α) in serum，and the scores of Visual Analogue Scale (VAS) were compared before and after treatment between the two groups. Results： The total effective rate was 98.11% in the combination group， higher than that of 86.79% in the control group， the difference being significant (P＜0.05). After treatment， the scores of ODI and VAS in the two groups were decreased when compared with those before treatment (P＜0.05)， and the scores of ODI and VAS in the combination group were lower than those in the control group (P＜0.05). After treatment，the levels of substance P and TNF-α in serum were decreased when compared with those before treatment (P＜0.05)，and the two levels in the combination group were lower than those in the control group (P＜0.05). Conclusion： Extracorporeal shock wave combined with internal heat acupuncture has a significant curative effect in the treatment of lower back myofasciitis， and can effectively relieve inflammation and pain symptoms of patients， and enhance the function of lower back muscle.