Abstract： Objective： To observe the clinical effect of Zaoshi Jianpi Decoction combined with Ethinyl Estradiol Cyproterone Tablets on polycystic ovary syndrome (PCOS) with phlegm-damp type. Methods：A total of 60 patients with PCOS with phlegm- damp type were selected and divided into the Chinese medicine group and the western medicine group according to the random number table method ， with 30 cases in each group. The western medicine group was given Ethinyl Estradiol Cyproterone Tablets，and the Chinese medicine group was treated with Zaoshi Jianpi Decoction combined with Ethinyl Estradiol Cyproterone Tablets. With a menstrual cycle as 1 course of treatment ， both groups were treated for 3 courses and followed up for 3 months. The clinical effects，traditional Chinese medicine (TCM) syndrome scores，levels of serum sex hormones including follicle stimulating hormone (FSH) and luteinizing hormone (LH)， and LH/FSH value were compared between the two groups. Results： After treatment， the total clinical effective rate was 93.33% in the Chinese medicine group， higher than that of 73.33% in the western medicine group (P＜0.05). After treatment， the scores of delayed menstruation， less menstrual blood or amenorrhea，vomiting and nausea and profuse phlegm，fullness and discomfort in the chest and hypochondrim， lassitude of spirit and fatigue， and excessive vaginal discharge in the two groups were decreased when compared with those before treatment (P＜0.05)，and the above 6 TCM syndrome scores in the Chinese medicine group were lower than those in the western medicine group (P＜0.05). Before and after treatment and between the two groups， there were no significant difference being found in the comparison of serum FSH levels (P＞0.05)；the serum LH levels and LH/FSH values in both groups were decreased when compared with those before treatment (P＜0.05)， and the serum LH level and LH/FSH value in the Chinese medicine group were lower than those in the western medicine group (P＜0.05). Conclusion：Zaoshi Jianpi Decoction combined with Ethinyl Estradiol Cyproterone Tablets has a significant curative effect on PCOS with phlegm- damp type， which can help mitigate the clinical symptoms of patients and improve the levels of serum sex hormones.