坤泰胶囊联合芬吗通治疗稽留流产清宫术后对子宫内膜修复的影响
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R714.21

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Effect of Kuntai Capsules Combined with Femoston on Endometrial Repair After Uterine Curettage for Missed Abortion
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    摘要:

    目的:观察坤泰胶囊联合芬吗通治疗稽留流产清宫术后对子宫内膜修复的临床疗效。方法:选择 因稽留流产接受清宫术治疗的患者93 例,按随机数字表法分为治疗组48 例与对照组45 例。对照组给予芬吗 通治疗,治疗组给予坤泰胶囊联合芬吗通治疗。治疗28 d 后,比较2 组临床疗效、阴道流血时间、月经复潮 时间、子宫内膜修复情况及卵巢功能。结果:治疗组总有效率为95.83%,对照组为82.22%,2 组比较,差异 有统计学意义(P<0.05)。术后,治疗组阴道流血时间、月经复潮时间短于对照组,差异均有统计学意 义(P<0.05)。治疗14 d,治疗组子宫动脉阻力指数(RI)、搏动指数(PI) 值均低于对照组(P<0.05),收 缩期最大流速(PSV)、子宫内膜厚度均大于对照组(P<0.05)。治疗28 d,2 组RI、PI 值均较治疗14 d 时降 低(P<0.05),PSV、子宫内膜厚度均较治疗14 d 时增加(P<0.05);且治疗组RI、PI 值均低于对照组(P< 0.05),PSV、子宫内膜厚度均大于对照组(P<0.05)。治疗后,2 组黄体生成素(LH)、孕酮(P) 水平较治 疗前降低(P<0.05),雌二醇(E2) 水平较治疗前升高(P<0.05);且治疗组LH、P 水平均低于对照组(P< 0.05),E2 水平高于对照组(P<0.05)。结论:坤泰胶囊联合芬吗通治疗稽留流产清宫术后患者疗效显著,可 缩短阴道流血时间,促进月经复潮,有助于修复子宫内膜,改善卵巢功能。

    Abstract:

    Abstract: Objective: To observe the clinical effect of the therapy of Kuntai Capsules combined with Femoston on endometrial repair after uterine curettage for missed abortion. Methods:A total of 93 patients who had undergone uterine curettage for missed abortion were selected and divided into the treatment group (48 cases) and the control group (45 cases) according to random number table method. The control group was treated with Femoston,and the treatment group was treated with Kuntai Capsules combined Femoston. After 28 days of treatment,the clinical effects,vaginal bleeding time,menstrual return time, endometrial repair and ovarian function were compared between the two groups. Results: The total effective rate was 95.83% in the treatment group and 82.22% in the control group,the difference being significant (P<0.05). After surgery, the vaginal bleeding time and menstrual return time in the treatment group were shorter than those in the control group,differences being significant (P<0.05). After 14 days of treatment,the resistance index (RI) and pulsation index (PI) values in the treatment group were lower than those in the control group (P<0.05),and the peak systotic relocity (PSV) and endometrial thickness were greater than those in the control group (P<0.05). After 28 days of treatment,the RI and PI values in both groups were decreased when compared with those had 14 days of treatment (P<0.05),and the PSV and endometrial thickness were augmented when compared with those had 14 days of treatment (P<0.05); the RI and PI values in the treatment group were lower than those in the control group (P<0.05),and the PSV and endometrial thickness were greater than those in the control group (P<0.05). After treatment,the luteinizing hormone (LH) and progesterone (P) levels in the two groups were decreased when compared with those before treatment (P<0.05), and the estradiol (E2) levels were increased when compared with those before treatment (P<0.05);the LH and P levels in the treatment group were lower than those in the control group (P<0.05),and the E2 level in the treatment group was higher than that in the control group (P<0.05). Conclusion: The therapy of Kuntai Capsules combined with Femoston has a significant therapeutic effect on patients who had undergone uterine curettage for missed abortion,which can shorten the time of vaginal bleeding, promote menstruation, and help repair endometrium and improve ovarian function.

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成彩云,马亚慧,胡方方.坤泰胶囊联合芬吗通治疗稽留流产清宫术后对子宫内膜修复的影响[J].新中医,2023,55(12):96-99

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  • 在线发布日期: 2023-06-27
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