Abstract：Zhangmen point (LR13) can be used to treat the spleen and stomach，liver and gallbladder， intestinal viscera，and heart system diseases，internal emergent cases，pediatric diseases，and surgical diseases. Analyzing and summarizing the positioning， acupuncture， moxibustion， and clinical application of Zhangmen point in Zhen Jiu Da Cheng (The Great Compendium of Acupuncture and Moxibustion)，which can provide reference for clinical application of Zhangmen point in treating diseases.