清肺化痰、通腑泻热法治疗脑卒中术后肺部感染痰热腑实证临床研究
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R743.3;R563.1

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Clinical Study on Method of Clearing Lung Heat and Resolving Phlegm, and Unblocking the Bowels and Discharging Heat for Pulmonary Infection with Phlegm- Heat and Bowel Excess Syndrome After Operation for Stroke
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    摘要:

    目的:观察清肺化痰、通腑泻热法治疗脑卒中术后肺部感染痰热腑实证的临床疗效。方法:选取 86 例脑卒中术后并发肺部感染痰热腑实证的患者作为研究对象,采用随机数字表法分为观察组与对照组各 43 例。对照组给予常规西医治疗,观察组在对照组的基础上给予清肺化痰、通腑泻热法中药治疗。比较 2 组治疗前后肺功能指标、临床肺部感染评分(CPIS)、炎症因子[血清C-反应蛋白(CRP)、白细胞介素 6(IL-6)、降钙素原(PCT)] 水平,并比较2 组临床症状体征消失时间及临床疗效。结果:治疗前,2 组用 力肺活量(FCV)、每分钟最大通气量(MVV)、呼气最高峰流速(PEF) 比较,差异无统计学意义(P> 0.05);治疗后,2 组FCV、MVV、PEF 水平均升高(P<0.05),且观察组高于对照组(P<0.05)。观察组患者 发热、咳嗽、咳痰及肺部湿啰音消失时间均短于对照组(P<0.05)。治疗前,2 组CPIS 评分和CRP、IL-6、 PCT 水平比较,差异无统计学意义(P>0.05);治疗后,2 组CPIS 评分和CRP、IL-6、PCT 水平均降低(P< 0.05),且观察组低于对照组(P<0.05)。观察组治疗总有效率95.35%,高于对照组79.07% (P<0.05)。结 论:清肺化痰、通腑泻热法治疗脑卒中术后肺部感染痰热腑实证患者疗效确切,可有效缓解患者的临床症状, 改善肺功能指标,减轻肺部感染,降低炎症因子水平。

    Abstract:

    Abstract:Objective:To observe the clinical effect of the method of clearing lung-heat and resolving phlegm, and unblocking the bowels and discharging heat for pulmonary infection with phlegm heat and bowel excess syndrome after operation for stroke. Methods:A total of 86 cases of patients with pulmonary infection with phlegm- heat and bowel excess syndrome after operation for stroke were selected as the study objects,and were divided into the observation group and the control group according to the random number table method,with 43 cases in each group. The control group was given routine western medicine treatment,and the observation group was additionally treated with Chinese medicine with the method of clearing lung- heat and resolving phlegm, and unblocking the bowels and discharging heat based on the treatment of the control group. Before and after treatment, the lung function indexes, the Clinical Pulmonary Infection Scores (CPIS), and the levels of inflammatory factors [C- reactive protein (CRP), interleukin 6 (IL- 6), and procalcitonin (PCT) in serum] were compared between the two groups. The disappearance time of clinical symptoms and the clinical effects were compared between the two groups. Results: Before treatment, there was no significant difference being found in the comparison of forced vital capacity (FCV),maximal voluntary ventilation (MVV) per minute,and peak expiratory flow rate (PEF) between the two groups (P>0.05). After treatment,the levels of FCV,MVV,and PEF in the two groups were increased (P<0.05), and the above levels in the observation group were higher than those in the control group (P<0.05). The disappearance time of fever,cough,sputum and pulmonary moist rales in the observation group was shorter than that in the control group (P<0.05). Before treatment, there was no significant difference being found in the comparison of CPIS scores,and the levels of CRP,IL-6,and PCT between the two groups (P>0.05). After treatment,CPIS scores,and the levels of CRP,IL-6,and PCT in the two groups were decreased (P<0.05),and the above indexes in the observation group were lower than those in the control group (P<0.05). The total effective rate was 95.35% in the observation group, higher than that of 79.07% in the control group (P<0.05). Conclusion:The method of clearing lung- heat and resolving phlegm,and unblocking the bowels and discharging heat has a definite curative effect in the treatment of patients with pulmonary infection with phlegm heat and bowel excess syndrome after operation for stroke,which can effectively relieve the clinical symptoms of patients,improve lung function indexes,and reduce the levels of pulmonary infection and inflammatory factors.

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王松鹤,周笑非,张亚丽,孟凡学,司建伟,金晓烨,赵新爱.清肺化痰、通腑泻热法治疗脑卒中术后肺部感染痰热腑实证临床研究[J].新中医,2023,55(13):62-66

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  • 在线发布日期: 2023-07-14
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