Abstract：Objective：To observe the clinical effect of Shenqi Jiangtang Granules in adjuvant therapy of type Ⅱ diabetes complicated with metabolism syndrome. Methods： A total of 103 patients with type Ⅱ diabetes complicated with metabolism syndrome were divided into the control group and the observation group according to the random number table method， with 51 and 52 cases in each group. The control group was given routine western medicine for treatment， and the observation group was additionally treated with Shenqi Jiangtang Granules based on the treatment of the control group. Before and after treatment， the indexes of blood glucose， the traditional Chinese medicine (TCM) syndrome scores， indexes of blood lipid，and indexes of islet β-cell function were compared between the two groups；the clinical effects and incidence of adverse reactions in the two groups were evaluated. Results： After treatment，the total effective rate was 92.31% in the observation group，higher than that of 76.47% in the control group (P＜0.05). After treatment，the levels of fasting blood glucose (FBG)，2-hour post-breakfast blood glucose (P2hBG) and hemoglobin A1c (HbA1c)， total cholesterol (TC)， triglyceride (TG) and lowdensity lipoprotein-cholesterol (LDC-C) in both groups were lower than those before treatment (P＜0.05)， the high-density lipoprotein cholesterol (HDL-C) levels were higher than those before treatment (P＜0.05)； the levels of indexes of blood glucose，TC，TG and LDL-C in the observation group were lower than those in the control group (P＜0.05)， and the HDL- C level was higher than that in the control group (P＜0.05). After treatment，the the index of homeostatic model assessment for β cell function (HOMA- β) levels in both groups were increased when compared with those before treatment (P＜0.05)， and the TCM syndrome scores and homeostatic model assessment of insulin resistance (HOMA- IR) levels were decreased (P＜0.05)； the HOMA- β level in the observation group was higher than that in the control group (P＜0.05)，and the TCM syndrome scores and HOMA-IR level were lower than those in the control group (P＜0.05). There was no significant difference being found in the comparison of incidence of adverse reactions between the two groups (P＞0.05). Conclusion： Shenqi Jiangtang Granules as an adjuvant therapy has a definite curative effect on type II diabetes complicated with metabolism syndrome， which can effectively improve the disorder of blood lipid and islet β-cell function of patients，and reduce the level of blood glucose with good safety.