Abstract： Objective： To observe the clinical effect of point application with Cinnamomi Cortex combined with Celecoxib Capsules for acute gouty arthritis of wind- cold- dampness impediment type. Methods：A total of 106 cases of patients with acute gouty arthritis of wind- cold- dampness impediment type were selected and divided into the control group and the observation group according to the random number table method，with 53 cases in each group. The control group was given the oral administration of Celecoxib Capsules， and the observation group was additionally treated with point application with Cinnamomi Cortex based on the treatment of the control group. Both groups were treated for 14 days. The clinical effects in the two groups were evaluated. Before and after treatment，traditional Chinese medicine (TCM) syndrome scores， scores of joint pain and swelling， erythrocyte sedimentation rate (ESR)， blood uric acid (BUA)，hypersensitive C-reactive protein (hs-CRP)，interleukin-1β (IL-1β)，interleukin-6 (IL-6)， and tumor necrosis factor- α (TNF- α) were compared between the two groups. The incidence of adverse reactions was observed. Results： The total effective rate was 92.45% in the observation group， higher than that of 75.47% in the control group，the difference being significant (P＜0.05). After treatment，TCM syndrome scores， joint pain scores， and joint swelling scores in the two groups were decreased when compared with those before treatment (P＜0.05)； TCM syndrome score， joint pain score， and joint swelling score in the observation group were lower than those in the control group (P＜0.05). After treatment， the levels of ESR， BUA， hs- CRP， IL- 1β， IL- 6， and TNF- α in the two groups were decreased when compared with those before treatment (P＜0.05)； the levels of ESR， BUA， hs- CRP， IL- 1β，IL- 6，and TNF- α in the observation group were lower than those in the control group (P＜0.05). There was no significant difference being found in the comparison of the incidence of adverse reactions between the two groups (P＞0.05). Conclusion： Point application with Cinnamomi Cortex combined with Celecoxib Capsules for acute gouty arthritis of wind-cold-dampness impediment type can improve clinical effects and clinical symptoms by regulating the inflammatory response of the body，with good safety.