Clinical Study on Shufeng Jiedu Capsules for Acute Exacerbation of Chronic Obstruc⁃ tive Pulmonary DiseaseClinical Study on Shufeng Jiedu Capsules for Acute Exacerbation of Chronic Obstruc⁃ tive Pulmonary Disease
Department of Respiratory Medicine,General Hospital of the Medical and Health Services Community of Shaoxing Second Hospital,Shaoxing Zhejiang 312000,China 在期刊界中查找 在百度中查找 在本站中查找
Department of Respiratory Medicine,General Hospital of the Medical and Health Services Community of Shaoxing Second Hospital,Shaoxing Zhejiang 312000,China 在期刊界中查找 在百度中查找 在本站中查找
Department of Respiratory Medicine,General Hospital of the Medical and Health Services Community of Shaoxing Second Hospital,Shaoxing Zhejiang 312000,China 在期刊界中查找 在百度中查找 在本站中查找
Department of Respiratory Medicine,General Hospital of the Medical and Health Services Community of Shaoxing Second Hospital,Shaoxing Zhejiang 312000,China 在期刊界中查找 在百度中查找 在本站中查找
Department of Respiratory Medicine,General Hospital of the Medical and Health Services Community of Shaoxing Second Hospital,Shaoxing Zhejiang 312000,China 在期刊界中查找 在百度中查找 在本站中查找
Department of Respiratory Medicine,General Hospital of the Medical and Health Services Community of Shaoxing Second Hospital,Shaoxing Zhejiang 312000,China 在期刊界中查找 在百度中查找 在本站中查找
Abstract:Objective:To observe the clinical effect of Shufeng Jiedu Capsules for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and its effect on inflammatory factors and lung function. Methods:A total of 100 cases of AECOPD patients were selected and divided into the observation group and the control group according to the random number table method,with 50 cases in each group. The control group was given routine western medicine treatment,and the observation group was additionally given the oral administration of Shufeng Jiedu Capsules based on the treatment of the control group. Both groups were treated for seven days as a course of treatment. After one course of treatment,the levels of lung function indexes [forced expiratory volume in the first second (FEV 1 ),FEV 1 /forced vital capacity (FVC)], inflammatory factors [interleukin-6 (IL-6),tumor necrosis factor-α (TNF-α),hypersensitive C-reactive protein (hs-CRP)],and the clinical effects were compared between the two groups. Results:The total effective rate was 92.00% in the observation group and 76.00% in the control group,the difference being significant (P<0.05). After treatment,the levels of IL-6,hs-CRP,and TNF-α in serum in the two groups were decreased when compared with before treatment (P<0.05), and the above indexes in the observation group were lower than those in the control group (P<0.05). After treatment,the levels of FEV 1 and FEV 1 /FVC in the two groups were increased when compared with those before treatment (P<0.05), and the above two indexes in the observation group were higher than those in the control group (P<0.05). Conclusion:Shufeng Jiedu Capsules has a significant curative effect in the treatment of AECOPD,which can reduce the levels of inflammatory factors in serum and effectively improve the lung function of patients.