Abstract：Objective：Toobservetheeffectofelectroacupuncturecomplicatedwiththoracic paravertebral block (TPVB) on postoperative rapid rehabilitation and comfort of patients undergoing thoracoscopic radical resection of lung cancer. Methods：A total of 120 patients undergoing thoracoscopic radical resection of lung cancer were randomly divided into the control group A，the control group B，the observation group， and the control group C，with 30 cases in each group. Among them，one subject in the control group A was excluded due to incomplete data collection. The control group A was given general anesthesia directly； the control group B was given general anesthesia after receiving TPVB；the observation group was treated with electroacupuncture to stimulate bilateral Zusanli point (ST 36)， Neiguan point (PC 6)， and Neima point，and combined with TPVB，followed by general anesthesia；the control group C was treated with electroacupuncture stimulation on bilateral non-meridian point，and combined with TPVB，followed by general anesthesia. For postoperative analgesia，all the four groups were given intravenous analgesia pump or tramadol. Compare the changes in relevant indicators during and after surgery among the four groups. Results：This study successfully included 119 eligible cases with complete data. During the time points of T 1 ，T 2 ，T 3 ，T 4 ，T 5 ，and T 6 ，the comparison of heart rate (HR) (excluding time period T 5 ) and mean arterial pressure (MAP) values in the four groups showed significance in the difference (P＜0.05)，and the HR and MAP values in the observation group were significantly lower than other three groups，the comparison between the each two groups showed significance in the difference (P＜0.05). The amount of remifentanil and vecuronium during operation，the recovery time and extubation time after operation in the four groups showed significance in the difference (P＜0.05). The amount of remifentanil and vecuronium during operation，the recovery time and extubation time after operation in the observation group were significantly less than the other three groups， the comparison showed significance in the difference (P＜0.05). The pressing times of analgesic pump in the observation group were less than the other three groups，and the removal time of the thoracic drainage tube， the first time of getting out of bed activity and the hospitalization time were all shorter than the other three groups，differences being significant (P＜0.05). During t 1 to t 5 periods after surgery，the comparison of Visual Analogue Scale (VAS) scores of rest and exercise in the four groups showed significance in the difference (P＜0.05). During t 1 to t 5 ，the VAS scores of rest and exercise in the observation group were lower than those in the other three groups， the comparison showed significance in the difference (P＜0.05). During the d 1 ， d 2 ， and d 3 periods， the Bruggrmann Confort Scals (BCS) scores among the four groups showed significance in the difference (P＜ 0.05). During d 1 and d 2 ，the incidence of nausea and vomiting in the four groups showed significance in the difference (P＜0.05). During d 2 and d 3 ，the BCS scores in the observation group were significantly higher than those in the other three groups (P＜0.05). During d 1 ，d 2 ，d 3 ，the incidence of nausea and vomiting in the observation group was significantly lower than those in the other three groups (P＜0.05). During d 1 and d 3 periods after surgery，White blood cell count (WBC) and neutrophil number were compared among the four groups，and the difference were statistically significant (P＜0.05). WBC and neutrophils in observation group were significantly lower than those in other groups，andthedifferencewerestatisticallysignificant(P＜ 0.05). Conclusion： Electroacupuncture stimulation of bilateral Zusanli ， Neiguan ， and Neima points combined with thoracic paravertebral block patients undergoing TPVB can significantly lower blood pressure and HR，alleviate postoperative pain，reduce the use of analgesics，shorten postoperative awakening and extubation time， reduce the incidence of nausea and vomiting， improve postoperative comfort， and shorten hospital stay，which can accelerate the process of postoperative recovery.