Clinical Study on Acupuncture at Jiaji Points with Panlong Needling Method Com⁃ bined with Levodopa and Benserazide Hydrochloride for Movement Disorders in Par⁃ kinson's Disease of Liver-Kidney Insufficiency Type
Abstract:Objective:To observe the clinical effect of acupuncture at Jiaji points (EX-B2) with the Panlong needling method combined with Levodopa and Benserazide Hydrochloride for movement disorders in Parkinson's disease of liver-kidney insufficiency type. Methods:A total of 102 cases of patients with Parkinson's disease of liver- kidney insufficiency type were divided into the control group and the observation group according to the random number table method,with 51 cases in each group. The control group was treated with Levodopa and Benserazide Hydrochloride,and the observation group was treated with acupuncture at Jiaji points with the Panlong needling method based on the treatment of the control group. Traditional Chinese medicine (TCM) syndrome scores, scores of Tinetti Performance Oriented Mobility Assessment (POMA), Barthel indexes, and electrophysiologic indexes of motor nerve were compared between the two groups before and after treatment. Clinical effects and the incidence of adverse reactions were evaluated in the two groups. Results:During treatment,3 cases fell off and 48 cases were completed in the control group;2 cases fell off and 49 cases were completed in the observation group. After treatment,the total effective rate was 87.76% in the observation,higher than that of 66.67% in the control group (P<0.05). After treatment, the scores of POMA (gait test and balance test) and Barthel indexes in the two groups were increased when compared with those before treatment (P<0.05),and the TCM syndrome scores were lower than those before treatment (P<0.05);the scores of POMA and Barthel indexes in the observation group were higher than those in the control group (P<0.05), and the TCM syndrome score in the observation group was lower than that in the control group (P<0.05). After treatment,the latency of the median nerve,ulnar nerve,tibial nerve,and common peroneal nerve in the control group was increased when compared with that before treatment (P<0.05); the latency of the median nerve, ulnar nerve, tibial nerve, and common peroneal nerve in the observation group was decreased when compared with that before treatment (P<0.05);after treatment,the above latency of motor nerves in the observation group was lower than that in the control group (P<0.05). After treatment, the amplitude of the median nerve,ulnar nerve,tibial nerve,and common peroneal nerve in the control group was decreased when compared with that before treatment (P<0.05);the amplitude of the median nerve,ulnar nerve,tibial nerve,and common peroneal nerve in the observation group was increased when compared with that before treatment (P<0.05); after treatment, the above amplitude of motor nerves in the observation group was higher than that in the control group (P<0.05). No severe adverse reactions happened in the two groups. Conclusion:Acupuncture at Jiaji points with the Panlong needling method combined with Levodopa and Benserazide Hydrochloride has a definite curative effect and high safety in the treatment of Parkinson's disease of liver-kidney insufficiency type and can improve the motor function of patients and reduce peripheral nerve damage.