Abstract: Objective: To observe the clinical effect of Ginkgolide Injection combined with Piracetam Injection for cerebral infarction with the qi deficiency and blood stasis syndrome at convalescence. Methods: A total of 90 cases of patients with cerebral infarction with the qi deficiency and blood stasis syndrome at convalescence were selected and divided into the control group and the treatment group according to the random number table method, with 45 cases in each group. Both groups were given conventional treatment and rehabilitation training;the control group was additionally treated with Piracetam Injection, and the treatment group was additionally treated with Ginkgolide Injection based on the treatment of the control group. Both groups were treated for 2 weeks. Clinical effects,the scores of Mini- Mental Status Exam (MMSE),National Institutes of Health Stroke Scale (NIHSS) and Modified Barthel Index (MBI), and the levels of neurofunctional indicators [serum glial fibrillary acidic protein (GFAP), neuronspecific enolase (NSE),brain-derived neurotrophic factors (BDNF),and vascular endothelial growth factors (VEGF)],inflammatory indicators [serum homocysteine (Hcy),Interleukin-6 (IL-6),Interleukin-8 (IL-8), and tumor necrosis factor- α (TNF- α)] and hemorheology indicators [hematocrit (HCT),low- shear whole blood viscosity (LSV),high-shear whole blood viscosity (HSV),and plasma viscosity (PSV)] were compared between the two groups. The incidence of adverse reactions was recorded. Results:After treatment,the total clinical effective rate was 86.67% in the treatment group,higher than that of 68.89% in the control group (P<0.05). The scores of MMSE and MBI in the two groups were increased when compared with those before treatment (P<0.05),and the scores of MMSE and MBI in the treatment group were higher than those in the control group (P<0.05). The scores of NIHSS in the two groups were decreased when compared with those before treatment (P<0.05),and the score of NIHSS in the treatment group was lower than that in the control group (P<0.05). The levels of GFAP,NSE,Hcy,IL-6,IL-8,and TNF-α in serum in the two groups were decreased when compared with those before treatment (P<0.05),and the levels of GFAP,NSE,Hcy,IL-6,IL-8,and TNF-α in serum in the treatment group were lower than those in the control group (P<0.05). The levels of BDNF and VEGF in serum in the two groups were increased when compared with those before treatment (P<0.05), and the levels of BDNF and VEGF in serum in the treatment group were higher than those in the control group (P<0.05). The levels of HCT,PSV,LSV,and HSV in the two groups were decreased when compared with those before treatment (P<0.05), and the levels of HCT,PSV,LSV,and HSV in the treatment group were lower than those in the control group (P< 0.05). During treatment,the incidence of adverse reactions was 6.67% in the treatment group and 11.11% in the control group, and the comparison between the two groups showed no significance in the difference (P>0.05). Conclusion: In the treatment of cerebral infarction with the qi deficiency and blood stasis syndrome at convalescence,Ginkgolide Injection combined with Piracetam Injection can reduce the inflammatory reactions of the body,improve hemorheology,neural function and cognitive function,and enhance the quality of life of patients. It has significant effects and good safety.