经-穴体外反搏治疗射血分数保留心力衰竭临床研究
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R541.6

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中山市卫生健康局科研项目(2021J143)


Clinical Study of Meridian- Point External Counter- Pulsation for Heart Failure with Preserved Ejection Fraction
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    摘要:

    目的:观察经-穴体外反搏治疗射血分数保留心力衰竭的临床疗效。方法:选取射血分数保留心力 衰竭患者72 例,采用随机数字表法分为对照组和试验组各36 例,治疗过程中对照组脱落4 例,试验组脱落 5 例。对照组给予西医规范化治疗,试验组在对照组基础上给予经-穴体外反搏治疗。比较2 组治疗前后中医 证候积分、N-末端脑利钠肽前体(NT-pro BNP) 水平,检测心肌收缩指数(ICON)、心输出量(CO)、心脏 指数(CI)。结果:治疗后,2 组中医证候积分较治疗前降低(P<0.05),且试验组中医证候积分低于对照 组(P<0.05)。治疗后,2 组NT-pro BNP 水平较治疗前降低(P<0.05);且试验组NT-pro BNP 水平低于对 照组(P<0.05)。治疗后,2 组ICON、CO、CI 较治疗前升高(P<0.05);且试验组ICON、CO、CI 高于对照 组(P<0.05)。结论:经-穴体外反搏治疗射血分数保留心力衰竭能改善临床症状,降低NT-pro BNP 水平,改 善心肌收缩功能。

    Abstract:

    Abstract: Objective: To observe the clinical effect of meridian- point external counter- pulsation on heart failure with preserved ejection fraction. Methods: A total of 72 patients with heart failure with preserved ejection fraction were selected and divided into the control group and the trial group according to the random number table method , with 36 cases in each group. During the treatment , 4 cases were dropped off in the control group and 5 cases in the trial group. The control group was given the standard treatment in western medicine, and the trial group was additionally treated with meridian- point external counter-pulsation based on the treatment of the control group. Before and after treatment,the traditional Chinese medicine syndrome (TCM) scores and the levels of N terminal pro B type natriuretic peptide (NTpro BNP) were compared between the two groups; the index of contractility(ICON),cardiac output (CO) and cardiac index (CI) in both groups were detected. Results:After treatment,the TCM syndrome scores in the two groups were decreased when compared with those before treatment (P<0.05), and the TCM syndrome scores in the trial group was lower than that in the control group (P<0.05). After treatment,the NT-pro BNP levels in both groups were decreased when compared with those before treatment (P<0.05); the NT-pro BNP level in the trial group was lower than that in the control group (P<0.05). After treatment, the ICON, CO and CI in both groups were increased when compared with those before treatment (P< 0.05); the ICON, CO and CI in the trial group were higher than those in the control group (P<0.05). Conclusion:The meridian-point external counter-pulsation can improve the clinical symptoms of patients with heart failure with preserved ejection fraction, reduce the NT- pro BNP level and enhance the myocardial contraction function.

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李双妍,李建功,李雪山.经-穴体外反搏治疗射血分数保留心力衰竭临床研究[J].新中医,2023,55(19):172-175

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  • 在线发布日期: 2023-10-17
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