Abstract： Objective： To observe the effect of the therapy of follow- up empowerment education combined with acupoint hot pressing with Chinese medicine packages on nausea and vomiting after radiotherapy and chemotherapy for cervical cancer. Methods： A total of 104 patients with cervical cancer receiving radiotherapy and chemotherapy were divided into the control group and the study group according to random number table method， with 52 cases in each group. At the same time of radiotherapy and chemotherapy， the control group was treated with Ondansetron Hydrochloride Injection， and the study group was given follow- up empowerment education combined with acupoint hot pressing with Chinese medicine packages. Both groups were intervened for 6 weeks. The incidence of nausea and vomiting， accompanying symptom scores，Exercise of Self-Care Agency Scare (ESCA) scores，and the incidence of adverse reactions were compared between the two groups. Results：After intervention，the incidence of nausea and vomiting in the study group was 38.46%，lower than that of 59.62% in the control group (P＜ 0.05). The scores of poor appetite，pain in the chest and rib-side，and stomach distension and stuffiness in the study group were lower than those in the control group (P＜0.05). The scores of health knowledge， self-care skills，self-care responsibility，and self-concept in both groups were increased when compared with those before intervention (P＜0.05)，and the scores of the above four ESCA items in the study group were higher than those in the control group (P＜0.05). No adverse reactions occurred in the study group， and the incidence of adverse reactions in the control group was 11.54%，the difference being significant (P＜0.05). Conclusion： The therapy of follow- up empowerment education combined with acupoint hot pressing with Chinese medicine packages can effectively improve the self- care ability of cervical cancer patients receiving radiotherapy and chemotherapy， relieve clinical symptoms， reduce the incidence of nausea and vomiting，and have great safety.