Abstract： Objective： To observe the clinical effect of the therapy of massage along meridians， collaterals and points combined with quick needling at Baliao point on post-stroke constipation and its effect on the gastrointestinal function. Methods：A total of 94 patients with post-stroke constipation were divided into the control group and the treatment group according to the random number table method ， with 47 cases in each group. The two groups were given routine treatment methods， the control group was additionally given quick needling at Baliao point and the treatment group was additionally treated with massage along meridians，collaterals and points based on the treatment of the control group. The clinical effects， traditional Chinese medicine (TCM) syndrome scores， scores of Patient Assessment of Constipation Symptoms (PAC- SYM)， and levels of bifidobacteria， motilin (MTL)， gastrin (GAS)， rectal resting pressure，anal resting pressure and anal systolic blood pressure of simulated defecation before and after treatment were compared between the two groups. Results：After treatment，the total effective rate was 91.49% in the treatment group， higher than that of 68.09% in the control group (P＜0.05). After treatment， the TCM syndrome scores， PAC- SYM scores and MTL levels in the two groups were decreased when compared with those before treatment (P＜0.05)，and the levels of bifidobacteria，GAS， rectal resting pressure，anal resting pressure and anal systolic blood pressure of simulated defecation were increased (P＜0.05)； the TCM syndrome score， PAC- SYM score and MTL level in the treatment group were lower than those in the control group (P＜0.05)，and the levels of bifidobacteria，GAS，rectal resting pressure，anal resting pressure and anal systolic blood pressure of simulated defecation were higher than those in the control group (P＜0.05). Conclusion：The therapy of massage along meridians，collaterals and points combined with quick needling at Baliao point has a definite curative effect on post- stroke constipation， which can adjust the levels of gastrointestinal hormones and improve the gastrointestinal function.