Abstract:Objective:To explore the medication rules of Professor YANG Xiangzheng in treating cough variant asthma in children,and provide diagnostic and therapeutic basis for the clinical treatment of cough variant asthma in Chinese medicine pediatrics. Methods: Professor YANG Xiangzheng's proven prescriptions for treating cough from August 2020 to August 2021 were collected and input into Microsoft Excel and the Traditional Chinese Medicine Inheritance Support System (V2.5) to calculate the frequency of Chinese medicines;statistical analysis of core combinations in those prescriptions was carried out by using Apriori algorithm and association rules (the support level was 0.6 and the confidence level was greater than or equal to 0.95); core combinations and new prescriptions and combinations were extracted based on unsupervised entropy hierarchical clustering method (the correlation degree was 6 and the penalty degree was 2). Results: A total of 217 prescriptions were collected and organized, involving 143 Chinese medicines. Among them,Glycyrrhizae Radix Et Rhizoma,Poria,Stemonae Radix,Schisandrae Chinensis Fructus, Armeniacae Semen Amarum, Citri Exocarpium Rubrum were Chinese medicines with higher using frequency. The common medicinal combinations were Glycyrrhizae Radix Et Rhizoma and Poria, Glycyrrhizae Radix Et Rhizoma and Stemonae Radix,Poria and Schisandrae Chinensis Fructus,Poria and Stemonae Radix, Glycyrrhizae Radix Et Rhizoma and Schisandrae Chinensis Fructus. A total of 10 core combinations and 5 new prescriptions were excavated. Conclusion: In the treatment of cough variant asthma in children,Professor YANG Xiangzheng takes dissolving phlegm and relieving cough and panting as the main treatment method; the five new prescriptions formed by internal correlation clustering respectively apply the methods of moistening the lung and constraining yin to stop cough,clearing heat and resolving phlegm,scattering wind and discharging heat,dispelling dampness and resolving phlegm,and warming yang and dissolving fluid retention,which can provide a reference for clinical treatment of cough variant asthma in children.