基于数据挖掘研究欧阳惠卿治疗痛经用药规律
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R271.11+3

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国家自然科学基金项目(81403423);欧阳惠卿全国名中医传承工作室建设项目(国中医药办人教函〔2018〕119号)


Medication Rule of OUYANG Huiqing in Treating Dysmenorrhea Based on Data Mining
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    摘要:

    目的:基于数据挖掘研究欧阳惠卿教授治疗痛经的用药规律。方法:收集广州中医药大学第一附 属医院全国名中医欧阳惠卿教授门诊的痛经病例,按纳入标准、排除标准进行筛选,建立欧阳惠卿痛经病例数 据库,运用中医传承辅助平台V3.0 的统计分析及方剂分析功能对其进行数据挖掘。结果:共纳入51 个病例, 涉及69 种中药,药物四气以温性为主,其次为平性、寒性,五味以为辛、苦、甘为主,归经以脾、肝、胃为 主,功效以理气、补虚、活血化瘀类为主,使用频次≥5 的高频药物共31 种,其中最核心的药物为木香,使用 频次≥25 的药物组合共16 个,其中含木香的组合共11 个,运用聚类分析得到可能的新方组合3 首。结论:欧 阳惠卿教授善用木香治疗女子痛经,处方用药顺应气血喜温恶寒的生理,以辛温苦甘为主,忌用大寒大热 之品。

    Abstract:

    Abstract: Objective: To study the medication rule of Professor OUYANG Huiqing in treating dysmenorrhea based on data mining. Methods: The cases of Professor OUYANG Huiqing, a famous Chinese medicine practitioner in The First Clinical Medical School of Guangzhou University of Chinese Medicine, in treating dysmenorrhea in the outpatient department, were collected. According to the inclusion and exclusion criteria, the case database of OUYANG Huiqing in treating dysmenorrhea was established,and the statistical analysis and prescription analysis function of Chinese Medicine Inheritance Assistance Platform V3.0 were used to carry out data mining. Results:A total of 51 cases were included, involving 69 kinds of Chinese herbs. In terms of four qi,the majority was warm,followed by balanced and cold. In terms of five flavors, the majority was acrid, bitter and sweet. In terms of channel entry, the majority was the spleen, liver and stomach. In terms of efficacy, the majority was rectifying qi, supplementing deficiency,invigorating blood and dissolving stasis. There were 31 kinds of high-frequency Chinese herbs with a frequency greater than or equal to 5,among which the core herb was Aucklandiae Radix. A total of 16 herbal combinations with a frequency greater than or equal to 25 were used,including 11 combinations containing Aucklandiae Radix. Three possible combinations of new prescription were obtained by cluster analysis. Conclusion:Professor OUYANG Huiqing makes good use of Aucklandiae Radix to treat dysmenorrhea in women. The medication conforms to the physiology of qi and blood preferring warm and being averse to cold, and the majority of four qi and five flavors is acrid, warm, bitter and sweet,those with extremely cold or hot property are forbiddened.

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王兰,陈婉莹,刘家骏,丰子仪,黄洁明.基于数据挖掘研究欧阳惠卿治疗痛经用药规律[J].新中医,2023,55(22):1-6

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  • 在线发布日期: 2023-11-28
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