Abstract:Objective:To observe the curative effect of the therapy of Modified Chaihu and Longgu Muli Decoction combined with scraping on ears on menopausal syndrome (with syndrome of liver constraint and kidney deficiency). Methods: A total of 120 patients with menopausal syndrome (with syndrome of liver constraint and kidney deficiency) were selected and divided into the routine group, the decoction group, the scraping group and the combination group according to the random number table method , with 30 cases in each group. The routine group was given routine western medicine for treatment; the decoction group was treated with routine western medicine and Modified Chaihu and Longgu Muli Decoction;the scraping group was treated with routine western medicine and scraping on ears,and the combination group was treated with routine western medicine, Modified Chaihu and Longgu Muli Decoction and scraping on ears. The four groups were treated for 3 months. The clinical effects in the four groups were evaluated; the traditional Chinese medicine syndrome scores, and levels of serum follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) were compared before and after treatment between the four groups; the incidence of adverse reactions was observed. Results: The comparison of the total effective rate between the four groups showed significance in the difference (P< 0.05); the total effective rate in the combination group was higher than that in the scraping group the routine group (P<0.05). After treatment, the scores of primary symptoms and secondary symptoms and the total scores in the four groups were decreased when compared with those before treatment (P<0.05), the above three scores in the combination group were lower than those in the other three groups (P<0.05); the above three scores in the decoction group were lower than those in the scraping group and the routine group (P<0.05), and the above three scores in the scraping group were lower than those in the routine group (P<0.05). After treatment,the levels of serum FSH and LH in the four groups were decreased when compared with those before treatment (P<0.05), the above two levels in the combination group were lower than those in the other three groups (P<0.05), the above two levels in the decoction group were lower than those in the scraping group and the routine group (P<0.05), and the above two levels in the scraping group were lower than those in the routine group (P<0.05). After treatment,the serum E2 levels in the four groups were increased when compared with those before treatment (P<0.05);the serum E2 level in the combination group was lower than those in the other three groups (P<0.05);the serum E2 level in the decoction group was higher than those in the scraping group and the routine group (P<0.05), and serum E2 level in the scraping group was higher than that in the routine group (P<0.05). There was no significant difference being found in the comparison of incidence of adverse reactions between the four groups (P>0.05). Conclusion:Both Modified Chaihu and Longgu Muli Decoction and scraping on ears can mitigate the clinical symptoms of patients with menopausal syndrome, and improve the levels of serum sex hormones. The former has a better curative effect than that of the latter. The combination of the two has a better effect and can also improve the clinical effect.