Abstract： Objective： To observe the clinical effect of the therapy of warming- needle moxibustion combined with Huoxue Tongbi Decoction on periarthritis of shoulder of wind-cold-damp type. Methods：A total of 96 patients with periarthritis of shoulder of wind-cold-damp type were selected，and divided into the combination group and the control group according to random number table method，with 48 cases in each group. The control group was treated with Huoxue Tongbi Decoction，and the combination group was treated with warming- needle moxibustion combined with Huoxue Tongbi Decoction. Both groups were treated for 4 weeks. The clinical effects were compared between the two groups， and the changes of shoulder joint function，present pain intensity (PPI)，Visual Analogue Scale (VAS)，Pain Rating Index (PRI)， traditional Chines medicine (TCM) symptom scores and 36- item Short Form Health Survey (SF- 36) were compared before and after treatment between the two groups. Results： The total effective rate was 93.75% in the combination group and 79.17% in the control group， the difference being significant (P＜ 0.05). After treatment，the scores of shoulder joint motion，pain，muscle strength and dimension of daily life in the two groups were increased when compared with those before treatment (P＜0.05)， and the above 4 scores in the combination group were higher than those in the control group (P＜0.05). After treatment，the scores of PPI，VAS and PRI in the two groups were decreased when compared with those before treatment (P＜0.05)，and the above three scores in the combination group were lower than those in the control group (P＜0.05). After treatment， the TCM symptom scores in both groups were decreased when compared with those before treatment (P＜0.05)， and the SF- 36 scores were increased when compared with those before treatment (P＜0.05)；the TCM symptom scores in the combination group were lower than those in the control group (P＜0.05)，and the SF- 36 score was higher than that in the control group (P＜0.05). Conclusion：The therapy of warming-needle moxibustion combined with Huoxue Tongbi Decoction can improve the curative effect，relieve pain，improve the shoulder joint function and quality of life.