中医穴位敷贴联合西药治疗老年帕金森病伴功能性便秘临床研究
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R742.5;R725.7

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Clinical Study on Chinese Medicine Point Application Combined with Western Medi⁃ cine for Senile Parkinson's Disease Complicated with Functional Constipation
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    摘要:

    目的:观察中医穴位敷贴联合西药治疗老年帕金森病(PD) 伴功能性便秘的疗效。方法:选 取80 例老年PD 伴功能性便秘患者,按随机数字表法分为观察组及对照组各40 例,观察组给予中医穴位敷贴 联合西药治疗,对照组仅给予西药治疗。比较2 组临床疗效及复发率,比较2 组治疗前后中医症状评分、生活 质量自评量表(PAC-QOL) 评分的变化。结果:观察组临床总有效率为95.00%,对照组为77.50%,2 组比 较,差异有统计学意义(P<0.05)。治疗后,2 组中医症状各项评分均较治疗前下降(P<0.05),观察组中医 症状各评分均低于对照组(P<0.05)。治疗后,2 组生理、担忧程度、社会心理、自身满意度的PAC-QOL 评 分及总分均较治疗前下降(P<0.05),观察组上述4 项评分及总分均低于对照组(P<0.05)。观察组停药1 个 月、3 个月后复发率均低于对照组,差异有统计学意义(P<0.05)。结论:中医穴位敷贴联合西药治疗老年 PD 伴功能性便秘可提升临床疗效,有效缓解便秘症状,提高生活质量,减少便秘复发率。

    Abstract:

    Abstract: Objective: To observe the curative effect of Chinese medicine point application combined with western medicine on senile Parkinson's disease (PD) complicated with functional constipation. Methods: A total of 80 cases of senile patients with PD complicated with functional constipation were selected and divided into the observation group and the control group according to the random number table method, with 40 cases in each group. The observation group was treated with Chinese medicine point application combined with western medicine, and the control group was only treated with western medicine. Clinical effects and the recurrence rates were compared between the two groups. Traditional Chinese medicine (TCM) symptom scores and the scores of Patient Assessment of Constipation Quality of Life (PAC- QOL) were compared between the two groups before and after treatment. Results: The total clinical effective rate was 95.00% in the observation group and 77.50% in the control group,the difference being significant (P<0.05). After treatment, each score of TCM symptoms in the two groups was decreased when compared with that before treatment (P<0.05),and each score in the observation group was lower than that in the control group (P<0.05). After treatment, the scores of physical discomfort, worries and discomfort, psychosocial discomfort, and treatment satisfaction, and the total scores of PAC-QOL in the two groups were decreased when compared with those before treatment (P<0.05),and the above four scores in the observation group were lower than those in the control group (P<0.05). The recurrence rates in the observation group were lower than those in the control group after medicine withdrawal for 1 month and 3 months (P<0.05). Conclusion: In the treatment of PD complicated with functional constipation, Chinese medicine point application combined with western medicine can further improve clinical effects,effectively relieve constipation symptom,enhance quality of life and reduce the recurrence rate of constipation.

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卞乐乐,王一栋,陈思思.中医穴位敷贴联合西药治疗老年帕金森病伴功能性便秘临床研究[J].新中医,2023,55(23):195-199

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  • 在线发布日期: 2023-12-13
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