Abstract： Objective： To observe the clinical effect of Buyang Huanwu Decoction combined with western medicine on cerebral infarction (CI) in recovery period with qi deficiency and blood stasis syndrome. Methods：A total of 62 cases of patients who were in the recovery period of CI with qi deficiency and blood stasis syndrome were selected and divided into the observation group and the control group according to the random number table method， with 31 cases in each group. The control group was treated with western medicine (Aspirin Enteric- Coated Tablets and Clopidogrel Bisulfate Tablets)，and the observation group was additionally treated with Buyang Huanwu Decoction based on the treatment of the control group. Both groups were treated for 14 days. Clinical effects，scores of National Institute of Health Stroke Scale (NIHSS)，the levels of hemorheological indicators and brain injury markers，and the incidence of adverse reactions were compared between the two groups. Results：After treatment，the total effective rate was 93.55% in the observation group，higher than that of 74.19% in the control group (P＜0.05). The scores of NIHSS in the two groups were decreased when compared with those before treatment (P＜0.05)，and the NIHSS score in the observation group was lower than that in the control group (P＜0.05). The levels of whole blood high- shear viscosity (HSV)， whole blood low- shear viscosity (LSV)， plasma viscosity (PSV)， and hematocrit (HCT) in the two groups were decreased when compared with those before treatment (P＜ 0.05)，and the above four levels in the observation group were lower than those in the control group (P＜ 0.05). The levels of brain derived neurotrophic factor (BDNF) in serum in the two groups were increased when compared with those before treatment (P＜0.05)，and the levels of neuron specific enolase (NSE) and central nervous system- specific protein (S100- β) in serum were decreased when compared with those before treatment (P＜0.05)；serum BDNF level in the observation group was higher than that in the control group (P＜0.05)， and the levels of NSE and S100- β in serum in the observation group were lower than those in the control group (P＜0.05). During treatment， the incidence of adverse reactions was 9.68% in the observation group and 6.45% in the control group， there being no significance in the difference (P＞ 0.05). Conclusion： Buyang Huanwu Decoction combined with western medicine has a definite curative effect on CI in recovery period with qi deficiency and blood stasis syndrome，and can effectively improve hemorheological indicators， regulate the level of brain injury markers， and promote neural function recovery，with good safety.