Abstract：Objective：To observe the clinical effect of the therapy of Jiangzhi Tongluo Soft Capsules and Guanxinning Tablets combined with western medicine on chronic stable angina pectoris of qi stagnation and blood stasis type and its influence on electrocardiogram indexes. Methods： A total of 138 patients with chronic stable angina pectoris of qi stagnation and blood stasis type were divided into the control group and the study group according to random number table method，with 69 patients in each group. The two groups were treated with conventional western medicine， and the study group was additionally treated with Jiangzhi Tongluo Soft Capsules and Guanxinning Tablets orally. Both groups were treated for 8 weeks. Before and after treatment，the frequency of angina pectoris and the duration of each angina pectoris attack were measured， and the traditional Chinese medicine syndrome scores were evaluated； 24-hour holter electrocardiogram was performed to compare the times of ST segment depression， the maximum ST segment depression and the total time of ST segment depression； the contents of N-terminal brain natriuretic peptide precursor (NT-proBNP) and homocysteine (Hcy) in serum were determined. The clinical effects and incidence of adverse reactions were compared between the two groups. Results ： After 8 weeks of treatment，the total effective rate was 92.75% in the study group，higher than that of 73.91% in the control group， the difference being significant (P＜0.05). The frequency of angina pectoris attack in the two groups were decreased when compared with those before treatment，and the duration of angina pectoris attack were shortened when compared with those before treatment，differences being significant (P＜0.05). The frequency of angina pectoris attack in the study group was lower than that in the control group， and the duration of angina pectoris attack was shorter than that in the control group， differences being significant (P＜0.05). The times of ST segment depression and the maximum ST segment depression in the two groups were decreased when compared with those before treatment，and the total time of ST segment depression were shortened when compared with those before treatment， differences being significant (P＜0.05). The time of ST segment depression in the study group was lower than that in the control group， the maximum ST segment depression was lower than that in the control group， and the total time of ST segment depression was shorter than that in the control group， differences being significant (P＜0.05). The contents of serum NT-proBNP and Hcy in the two groups were decreased when compared with those before treatment (P＜0.05). The contents of serum NT-proBNP and Hcy in the study group were lower than those in the control group (P＜0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05). Conclusion： The therapy of Jiangzhi Tongluo Soft Capsules and Guanxinning Tablets combined with western medicine can relieve the clinical symptoms of chronic stable angina pectoris of qi stagnation and blood stasis type， improve the heart function，protect the myocardium，and do not increase the risk of medication.