Abstract：Objective：To observe the intervention effect of moxibustion at governor vessel in dog days and non - dog days on patients with yang-deficiency constitution. Methods： A total of 120 patients with yang-deficiency constitution were divided into the moxibustion at governor vessel in dog days group，the moxibustion at governor vessel in non-dog days group and the Jinkui Shenqi Pills group according to the random number table method， with 40 cases in each group. The moxibustion at governor vessel in dog days group was respectively given moxibustion at governor vessel on the first day of the beginning，middle and end of dog days； the moxibustion at governor vessel in non-dog days group was treated with moxibustion at governor vessel in non-dog days；the Jinkui Shenqi Pills group was given oral administration of Jinkui Shenqi Pills for treatment. The clinical effects，and the scores of yang-deficiency constitution and degree of intolerance of cold before treatment，at the end of treatment，three months after treatment and six months after treatment were respectively compared between the two groups. Results： The total effective rate was 87.50% in the moxibustion at governor vessel in dog days group， higher than that of 75.00% in the moxibustion at governor vessel in non-dog days group and 67.50% in the Jinkui Shenqi Pills (P＜0.05). The scores of yang-deficiency constitution and degree of intolerance of cold at the end of treatment， three months after treatment and six months after treatment in the three groups were respectively lower than those before treatment (P＜0.05)， and the above scores in the moxibustion at governor vessel in dog days group were respectively lower than those in the moxibustion at governor vessel in non-dog days group and the Jinkui Shenqi Pills (P＜0.05). Conclusion： The therapies of moxibustion at governor vessel in dog days， moxibustion at governor vessel in non-dog days and oral administration of Jinkui Shenqi Pills can all effectively improve the yang-deficiency constitution of patients，and reduce the degree of intolerance of cold. Among them， the moxibustion at governor vessel in dog days has the best intervention effect on yang-deficiency constitution.