Abstract: This paper introduces Professor WAN Donggui's clinical experience in treating female glandular nodules based on the idea of "yang transforming into qi, while yin constituting form". Professor WAN Donggui believes that thyroid, breast nodules, uterine fibroids, ovarian cysts and other common female gland nodules are highly correlated,whose core pathogenesis is insufficient transformation of yang into qi, and qi constituting form too much. WAN puts forward the basic treatment of warming and supplementing yang qi to cure its root,soothing the liver and rectifying qi to cure its cause,and dissolving phlegm and dissipating stasis to treat the branch, and is modified according to different syndromes. To warm and supplement yang qi,Jingui Shenqi Pills and Yougui Pills are often used and modified. To soothe the liver and rectify qi, Bupleuri Radix, Aurantii Fructus, Curcumae Radix and Cyperi Rhizoma are often used. To dissolve phlegm and dissipate stasis, triple medicine of Trichosanthis Pericarpium- Ranunculi Ternati Radix-Cremastrae Pseudobulbus Pleiones Pseudobulus are often used as to dissolve phlegm,and Chuanxiong Rhizoma and Salviae Chinensis Herba are used to dissolve stasis;and if phlegm blended with stasis,worm medicinals are used as appropriate. The above treatment often leads to a great therapeutic effect.