Abstract: Objective: To observe the effect of the therapy of Shengmai Decoction combined with Qianjin Weijing Decoction on the lung function and quality of life of patients after surgery of lung cancer. Methods: A total of 104 cases of patients receiving thoracoscopic radical resection of lung cancer were selected and divided into the treatment group and the control group according to the random number table method, with 52 cases in each group. The control group was given routine symptomatic treatment and breathing exercises for treatment after surgery, and the treatment group was additionally treated with Shengmai Decoction combined with Qianjin Weijing Decoction based on the treatment of the control group. The two groups were treated until the seventh day after surgery. The clinical effects in the two groups were evaluated at the seventh day after surgery;the traditional Chinese medicine (TCM) syndrome scores,lung function and quality of life at the first day and seventh day after surgery were respectively compared between the two groups. Results:At the seventh day after surgery,the total effective rate was 96.15% in the treatment group, higher than that of 82.69% in the control group, differences being significant (P< 0.05). The TCM syndrome scores were decreased in both group compared with those at the first day after surgery, and the TCM syndrome score in the treatment group was lower than that in the control group, differences being significant (P<0.05). The forced vital capacity (FVC), forced expiratory volume in one second (FEV1),and FEV1/FVC in the two groups were increased when compared with those at the first day after surgery, and the FVC, FEV1 and FEV1/FVC in the treatment group were higher than those in the control group, differences being significant (P<0.05). The scores of mental function, physical function, social function and material life in the two groups were increased when compared with those at the first day after surgery (P<0.05), and the above four scores in the treatment group were higher than those in the control group, differences being significant (P<0.05). Conclusion: The therapy of Shengmai Decoction combined with Qianjin Weijing Decoction can effectively mitigate the clinical symptoms of patients after surgery of lung cancer,and improve the lung function and quality of life.