Abstract： Objective： To observe the clinical effect of the therapy of Compound Hongteng Mixture combined with Drospirenone and Ethinylestradiol Tablets and Fuyankang Capsules on patients after hysteroscopic endometrial polypectomy. Methods：A total of 80 patients with endometrial polyps of dampheat with blood stasis type were selected and randomly divided into the control group and the combination group，with 40 cases in each group. The two groups were given hysteroscopic endometrial polypectomy for treatment， after which the two groups were treated with Drospirenone and Ethinylestradiol Tablets and Fuyankang Capsules and the combination group was additionally treated with Compound Hongteng Mixture. The two groups were treated for three menstrual cycles and followed up for 3 months. The traditional Chinese medicine (TCM) syndrome scores were evaluated before and after treatment； the menstruation recovery was observed by recording the menstrual period，menstrual volume and endometrial thickness； the levels of sex hormones， including estradiol (E2)， luteinizing hormone (LH) and follicle- stimulating hormone (FSH)，and of inflammatory factors，including C-reactive protein (CRP) and interleukin- 4 (IL- 4) were detected. The clinical effects，improvement rate of menstruation，incidence of adverse reactions and recurrence rate of endometrial polyps were counted. Results：After treatment，the total clinical effective rate was 95.00% in the combination group，higher than that of 75.00% in the control group，the difference being significant (P＜0.05). The TCM syndrome scores in the two groups were decreased when compared with those before treatment，and the TCM syndrome score in the combination group was lower than that in the control group (P＜0.05). The menstrual period in the two groups were shortened when compared with those before treatment， the menstrual volume were reduced when compared with those before treatment， and the endometrial thickness were thinner than those before treatment， differences being significant (P＜0.05). The menstrual period in the combination group was shorter than that in the control group，the menstrual volume was less than that in the control group，and the endometrial thickness was thinner than that in the control group， differences being significant (P＜0.05). The improvement rate of menstruation in the combination group was higher than that in the control group (P＜0.05). The levels of serum E2，LH and FSH in the two groups were decreased when compared with those before treatment (P＜ 0.05)，and the above levels in the combination group were lower than those in the control group (P＜0.05). The serum CRP levels in the two groups were decreased when compared with those before treatment， and the serum IL-4 levels were increased when compared with those before treatment，differences being significant (P＜0.05). The serum CRP level in the combination group was lower than that in the control group，and the serum IL- 4 level was higher than that in the control group，differences being significant (P＜0.05). There was no significant difference being found in the comparison of incidence of adverse reactions between the two groups (P＞0.05). After follow- up for 3 months， the recurrence rate in the combination group was lower than that in the control group (P＜0.05). Conclusion： The therapy of Compound Hongteng Mixture combined with Drospirenone and Ethinylestradiol Tablets and Fuyankang Capsules has a good curative effect on patients after hysteroscopic endometrial polypectomy，which can reduce the menstrual volume，regulate the levels of sex hormones，mitigate the inflammatory responses and effectively prevent the recurrence of polyps with good safety.