针刺辅助治疗脊髓损伤性截瘫临床研究
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R473.6;R246.2

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Clinical Study on Acupuncture Assisted Treatment for Paraplegia of Spinal Cord Injury
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    摘要:

    目的:观察针刺辅助治疗脊髓损伤性截瘫的临床疗效及对肢体运动功能的影响。方法:采用随机 数字表法将132 例脊髓损伤性截瘫患者分为观察组、对照组各66 例。2 组均给予常规药物治疗,对照组在常 规药物基础上给予康复训练治疗,观察组在对照组基础上给予针刺辅助治疗,2 组均连续治疗3 个月。比较 2 组临床疗效及治疗前后改良Barthel 指数评定量表(MBI)、美国损伤分级(ASIA)、汉密尔顿抑郁量 表(HAMD)、汉密尔顿焦虑量表(HAMA)、世界卫生组织生存质量测定量表(WHOQOL-BREF) 评分及血清 神经生长因子(NGF)、脑源性神经生长因子(BDNF)、5-羟色胺(5-HT) 水平。结果:治疗期间,对照组脱 落3 例,完成研究63 例。治疗后,观察组总有效率95.45%,高于对照组84.13% (P<0.05)。2 组治疗后 BMI、ASIA、WHOQOL-BREF 评分及血清NGF、BDNF、5-HT 水平均较治疗前升高(P<0.05),HAMD、 HAMA 评分降低(P<0.05);观察组治疗后BMI、ASIA、WHOQOL-BREF 评分及血清NGF、BDNF、5-HT 水 平高于对照组(P<0.05),HAMD、HAMA 评分低于对照组(P<0.05)。结论:中医针刺辅助治疗脊髓损伤性 截瘫疗效确切,能够通过调节患者神经递质水平来改善肢体运动功能,缓解患者负性情绪与提高生活质量。

    Abstract:

    Abstract:Objective:To observe the clinical effect of acupuncture assisted treatment for paraplegia of spinal cord injury and its effect on limb motor function. Methods:A total of 132 patients with paraplegia of spinal cord injury were divided into the observation group and the control group according to the random number table method, with 66 cases in each group. Both groups were treated with conventional drugs; the control group received rehabilitation training based on conventional drugs, and the observation group received acupuncture assisted treatment based on the treatment of the control group. Both groups received continuous treatment for 3 months. The clinical effects, the scores of Modified Barthel Index (MBI), American Spinal Injury Association (ASIA), Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA),and World Health Organization's Quality of Life Questionnaire (WHOQOL-BREF),and the levels of nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), and serotonin (5- HT) in serum were compared between the two groups. Results:During treatment,3 cases fell off and 63 cases were completed in the control group. After treatment, the total effective rate was 95.45% in the observation group, higher than that of 84.13% in the control group (P<0.05). After treatment, the scores of BMI, ASIA and WHOQOL- BREF, and levels of NGF, BDNF and 5- HT in serum in the two groups were increased when compared with those before treatment(P<0.05), and the scores of HAMD and HAMA were decreased (P<0.05). After treatment, the scores of BMI, ASIA and WHOQOL- BREF, and the levels of NGF,BDNF and 5- HT in serum in the observation group were higher than those in the control group(P<0.05), and the HAMD and HAMA scores were lower than those in the control group(P<0.05). Conclusion: Acupuncture in Chinese medicine has a definite curative effect on paraplegia of spinal cord injury, which can regulate the neurotransmitter levels, improve limb motor function, alleviate negative emotions,and improve quality of life.

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吴淑俭,吴李秀.针刺辅助治疗脊髓损伤性截瘫临床研究[J].新中医,2024,56(5):142-146

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  • 在线发布日期: 2024-03-14
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