补肺温肾汤联合穴位埋针治疗阳虚水泛证肺胀临床研究
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R 256.14

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Clinical Study on Bufei Wenshen Decoction Combined with Catgut Embedment in Point for Lung Distension with Syndrome of Edema due to Yang Deficiency
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    摘要:

    目的:观察补肺温肾汤联合穴位埋针治疗阳虚水泛证肺胀的临床效果。方法:选择96 例阳虚水泛 证肺胀患者作为研究对象,随机分为联合组和对照组各48 例。对照组给予常规西医治疗,联合组在常规西医 治疗基础上给予补肺温肾汤内服联合穴位埋针治疗。连续治疗2 周后,比较2 组临床疗效、中医证候评分、呼 吸困难程度[改良版英国医学研究委员会呼吸困难量表(mMRC) 评分]、生活质量[慢阻肺自我评估问卷(CAT) 评分]、肺功能[用力肺活量(FVC)、第1 秒用力呼气量(FEV1)、FEV1 /FVC]、心功能[左心室射血分 数(LVEF) ]和不良反应发生率。结果:治疗后,联合组总有效率为93.75%,对照组为79.17%,2 组比较, 差异有统计学意义(P<0.05)。治疗后,2 组中医证候评分、mMRC 评分、CAT 评分均较治疗前降低(P< 0.05),且联合组中医证候、mMRC、CAT 评分均低于对照组(P<0.05)。治疗后,2 组FVC、FEV1、FEV1/ FVC 水平均较治疗前升高(P<0.05),且联合组3 项肺功能指标均高于对照组(P<0.05)。治疗后,2 组 LVEF 水平较治疗前升高(P<0.05),且联合组LVEF 水平高于对照组(P<0.05)。联合组不良反应发生率为 8.33%,对照组为6.25%,2 组比较,差异无统计学意义(P>0.05)。结论:补肺温肾汤联合穴位埋针治疗阳虚 水泛证肺胀可进一步减轻临床症状,改善心肺功能,提高生活质量,且安全性良好。

    Abstract:

    Abstract: Objective: To observe the clinical effect of the therapy of Bufei Wenshen Decoction combined with catgut embedment in point on lung distension with syndrome of edema due to yang deficiency. Methods: A total of 96 patients with lung distension with syndrome of edema due to yang deficiency were selected as the study objects and randomly divided into the combination group and the control group,with 48 cases in each group. The control group was given conventional western medicine, and the combination group was additionally treated with Bufei Wenshen Decoction combined with catgut embedment in point based on the treatment of conventional western medicine. After two weeks of treatment, the clinical effects, traditional Chinese medicine syndrome (TCM) scores, dyspnea symptom degree by modified Medical Research Council (mMRC), quality of life by COPD Assessment Test (CAT), lung function,including forced vital capacity (FVC),forced expiratory volume in one second (FEV1) and FEV1/ FVC, heart function by left ventricular ejection fraction (LVEF), and incidence of adverse reactions were compared between the two groups. Results:After treatment,the total effective rate was 93.75% in the combination group and 79.17% in the control group, the difference being significant (P<0.05). After treatment,the TCM syndrome scores,mMRC scores and CAT scores in the two groups were decreased when compared with those before treatment (P<0.05), and the above three scores in the combination group were lower than those in the control group (P<0.05). After treatment,the levels of FVC,FEV1 and FEV1 /FVC in the two groups were increased when compared when compared with those before treatment (P<0.05), and the above three lung function indexes in the combination group were higher than those in the control group (P<0.05). After treatment, the LVEF levels in the two groups were increased when compared with those before treatment (P<0.05),and the LVEF level in the combination group was higher than that in the control group (P<0.05). The incidence of adverse reactions was 8.33% in the combination group and 6.25% in the control group,there being no significant difference between the two groups (P> 0.05). Conclusion:The therapy of Bufei Wenshen Decoction combined with catgut embedment in point for patients with lung distension with syndrome of edema due to yang deficiency, can further relieve symptoms,improve lung function and heart function,and enhance quality of life,with great safety.

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许敏利,倪岚,朱梦婷,叶凯梦.补肺温肾汤联合穴位埋针治疗阳虚水泛证肺胀临床研究[J].新中医,2024,56(6):80-84

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  • 在线发布日期: 2024-03-26
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