Abstract： Objective： To observe the clinical effect of the therapy of modified “Qianjin Weijing Decoction combined with Dachengqi Decoction” on stroke complicated with pulmonary infection with syndrome of dual deficiency of qi and yin and syndrome of phlegm-heat in the lung. Methods： A total of 96 cases of patients with stroke complicated with pulmonary infection with syndrome of dual deficiency of qi and yin and syndrome of phlegm-heat in the lung were selected and divided into the control group and the observation group according to the random number table method， with 48 cases in each group. The control group was treated with routine western medicine，and the observation group was additionally given modified “Qianjin Weijing Decoction combined with Dachengqi Decoction” for treatment based on the treatment of the control group. The two groups were treated for 14 days. The clinical effects，improvement time of clinical symptoms and signs， clinical pulmonary infection scores (CPIS)， levels of inflammation indexes [white blood cell (WBC) count， percentage of neutrophil granulocytes (NEUT% )， procalcitonin (PCT)，C-reactive protein (CRP)，interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α)] and incidence of adverse reactions were compared between the two groups. Results：After treatment，the total effective rate was 97.92% in the observation group，higher than that of 85.42% in the control group (P＜0.05). The disappearance time of cough， heat and lung rales and recovery time of normal chest radiograph in the observation group were shorter than those in the control group (P＜0.05). The CPIS scores in the two groups were decreased when compared with those before treatment (P＜0.05)， and the CPIS score in the observation group was lower than that in the control group (P＜0.05). The levels of WBC，NEUT%，PCT， CRP，IL-6 and TNF-α in the two groups were decreased when compared with those before treatment (P＜ 0.05)， and the above six levels in the observation group were lower than those in the control group (P＜ 0.05). During treatment， the incidence of adverse reactions was 10.42% in the observation group， and 6.25% in the control group，there being no significance in the difference (P＞0.05). Conclusion：Based on the routine western medicine，the therapy of modified“Qianjin Weijing Decoction combined with Dachengqi Decoction”has a significant curative effect on stroke complicated with pulmonary infection with syndrome of dual deficiency of qi and yin and syndrome of phlegm-heat in the lung， which can promote the improvement of clinical symptoms and reduce the inflammatory responses of the body with great safety.