Abstract： Based on the concept of prevent disease before it arises in Chinese medicine， this article proposes that attention should be paid to the role of time in the process of stroke occurrence. Based on the changes of healthy qi and pathogenic qi， as well as the physiology of zang-fu organs， the process from health status to stroke onset can be divided into three stages based on time axis： "injury-generationmanifestation"， and the prevention should be carried out in stages according to the characteristics of different stages. It is proposed that the period of injury to the healthy qi is at the beginning of stroke，with the accumulation of injury to healthy qi and loss of zang-fu organs over time as the pathogenesis. The main strategy should be to carry out health preservation before illness，taking into account factors such as diet， emotions， and exercise to protect healthy qi and prevent its injury. The endogenous period of pathogenic factors is the stage of disease development， with wind， fire， phlegm， and blood stasis as the main pathogenic factors； the disease prevention and regulation should be carried out， and methods such as dietary therapy should be used to eliminate internal pathogens and improve constitution. The symptom exposure period indicates the omen of stroke， so it is advisable to treat with a few symptoms， take treatment as prevention， combine prevention and treatment， and take acupuncture and moxibustion， medicine and other methods for timely treatment to prevent it from further developing into stroke.