Objective： To observe the curative effect of Shumian Capsules combined with Zopiclone Tablets for insomnia and its effect on sleep quality and psychological state. Methods：A total of 106 patients with insomnia were selected and divided into the control group and the trial group according to the random number table method，with 53 cases in each group. The control group was treated with Zopiclone Tablets， and the trial group was treated with Shumian Capsules combined with Zopiclone Tablets. Both groups were treated continuously for eight weeks. The changes in traditional Chinese medicine (TCM) syndrome scores， sleep quality [Pittsburgh Sleep Quality Index (PSQI) scores]，psychological state [Self-Rating Anxiety Scale (SAS)， and Self-Rating Depression Scale (SDS)]， and thyroid function index values [triiodothyronine (T3)， thyroxine (T4)， and thyroid-stimulating hormone (TSH)] before and after treatment， as well as the clinical effects were compared in the two groups. Results：The total clinical effective rate was 96.23% in the trial group， and 84.91% in the control group， the difference being significant (P＜0.05). After treatment， the TCM syndrome scores and PSQI scores in the two groups were decreased when compared with those before treatment (P＜0.05)， and the TCM syndrome score and PSQI score in the trial group were lower than those in the control group (P＜0.05). After treatment，the SAS and SDS scores in the two groups were decreased when compared with those before treatment (P＜0.05)，and the SAS and SDS scores in the trial group were lower than those in the control group (P＜0.05). After treatment， the T3， T4， and TSH index values in the two groups were decreased when compared with those before treatment (P＜0.05)，and the T3， T4， and TSH index values in the trial group were lower than those in the control group (P＜0.05). Conclusion：Shumian Capsules and Zopiclone Tablets has a definite curative effect on insomnia，which is beneficial for alleviating clinical symptoms，improving the psychological state and sleep quality of patients， and effectively regulating thyroid hormone levels.