Abstract： Objective： To observe the clinical effect of the adjuvant treatment of Wenglitong Capsules on patients with benign prostatic hyperplasia (BPH) after transurethral resection of the prostate (TURP). Methods：A total of 82 BPH patients after TURP were selected and divided into the observation group and the control group according to the random number table method，with 41 cases in each group. The control group was treated with routine interventions and Tamsulosin Hydrochloride Sustained Release Tablets after TURP，and the observation group was additionally treated with Wenglitong Capsules after TURP based on the treatment of the control group. The clinical effects in both groups were evaluated； the traditional Chinese medicine (TCM) syndrome scores， International Prostate Symptom Scores (IPSS) and scores of Quality of Life (QOL) were compared before and after treatment between the two groups； the levels of serum testosterone (T)，luteinizing hormone (LH) and prolactin (PRL) were detected；the prostate size was examined by B-mode ultrasound；the prostate volume (PV) was calculated；the residual urine volume (RV) and maximum urine flow rate (Qmax) were measured，and the adverse reactions were observed. Results： The total effective rate was 95.12% in the observation group， higher than that of 78.05% in the control group (P＜0.05). After treatment，the IPSS and TCM syndrome scores in both groups were reduced when compared with those before treatment， and the QOL scores were up-regulated when compared with those before treatment (P＜0.05)；the IPSS and TCM syndrome scores in the observation group were lower than those in the control group， and the QOL score was higher than that in the control group (P＜0.05). After treatment，the levels of PV and RV in both groups were dwindled when compared with those before treatment， and the Qmax levels were elevated when compared with those before treatment (P＜0.05)； the levels of PV and RV in the observation group were lower than those in the control group，and the Qmax level was higher than that in the control group (P＜0.05). After treatment，the levels of T and PRL in the two groups were increased when compared with those before treatment， and the LH levels were decreased when compared with those before treatment (P＜0.05)； the levels of T and PRL in the observation group were higher than those in the control group，and the LH level was lower than that in the control group (P＜ 0.05). There was no significant difference being found in the comparison of incidence of adverse reactions between the two groups (P ＞0.05). Conclusion：The adjuvant treatment of Wenglitong Capsules has a great clinical effect on BPH after TURP， which can improve the symptoms， regulate the levels of hormones， help enhance the quality of life and RV，and reduce the PV with no significant adverse reactions.