Objective:To observe the effect of heat-sensitive moxibustion on recovery of gastrointestinal function after laparoscopic hepatectomy. Methods: A total of 74 patients with primary liver cancer who underwent laparoscopic hepatectomy were selected and randomly divided into the trial group and the control group, with 37 cases in each group, using a random number table method. The control group received routine perioperative care,and the trial group received heat-sensitive moxibustion intervention in addition to the treatment of the control group. The first postoperative anal exhaust and defecation time, scores of Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep) questionnaire after surgery, incidence of postoperative adverse reactions, postoperative gastrointestinal rehabilitation effects, and hospitalization time were compared between the two groups. Results:The total effective rate was 94.60% in the trial group, and 83.78% in the control group, the difference being significant (P<0.05). The first postoperative anal exhaust time and defecation time in the trial group were shorter than those in the control group, differences being significant (P<0.05). After surgery, the average FACT-Hep score in the trial group was (129.65±3.36) points, and (113.68±4.65) points in the control group, the difference being significant (P<0.05). The incidence of abdominal pain,bloating,and nausea and vomiting in the trial group was 13.51%, 18.92%, and 8.11%, respectively, and 35.14%, 48.65%, and 27.03% in the control group respectively, the difference being significant (P<0.05). The average hospitalization time in the trial group was shorter than that in the control group, the difference being significant (P<0.05). Conclusion: Heat-sensitive moxibustion therapy can promote postoperative anal ventilation and defecation in patients with laparoscopic hepatectomy, improve postoperative quality of life, promote postoperative gastrointestinal function recovery, shorten hospitalization time, and have a relatively low incidence of adverse reactions.