Abstract：Objective：To observe the distribution rules of traditional Chinese medicine syndrome types of skin pruritus in uremic patients undergoing peritoneal dialysis and its influencing factors. Methods： The clinical data of 235 uremic patients undergoing peritoneal dialysis were retrospectively analyzed，and they were divided into the pruritus group and non-pruritus group according to pruritus profile， with 112 and 123 in each group. The distribution of traditional Chinese medicine syndrome types and differences of laboratory indexes [hemoglobin (Hb)， alkaline phosphatase (ALP)， prealbumin (PAB)， low-density lipoprotein cholesterol (LDL-C)， cystatin C (CysC)， β2-microglobulin (β2-MG)， serum transferrin (TRF)， C-reactive protein (CRP)， potassium (K)， magnesium (Mg)， phosphorus (P)， calcium (Ca)， intact parathyroid hormone (iPTH)， serum albumin (Alb)， uric acid (UA)， blood urea nitrogen (BUN)， creatinine (Cr)， triglyceride (TG)， total cholesterol (TC)， blood glucose and body mass index (BMI)] were compared between the two groups. Results： The proportion of male， diabetes， non-working patients and using Pregabalin or Gabapentin Capsules in the pruritus group was respectively higher than that in the nonpruritus group， the difference being significant (P＜0.05). The levels of CysC， CRP， P and Ca in pruritus group were higher than those in non-pruritus group， differences being significant (P＜0.05). There was significant difference being found in the comparison of distribution of blood stasis syndrome between the two groups (P＜0.05)； there was no significant difference being found in the comparison of distribution of remaining traditional Chinese medicine syndrome types (P＞0.05). The results of multivariate logistic regression model showed that diabetes and elevated levels of CRP，P were the influencing factors of skin pruritus. Conclusion： The distribution of traditional Chinese medicine syndrome types in uremic pruritus patients undergoing peritoneal dialysis is mainly the blood stasis syndrome， and diabetes and elevated levels of CRP，P were the influencing factors of skin pruritus.