揿针联合清肺健脾汤治疗脾气亏虚兼痰热壅肺型老年社区获得性肺炎临床研究
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R563.1

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2021年镇海区公益类科技项目(镇科〔2021〕15号)


Clinical Study on Thumb-Tack Needling Combined with Qingfei Jianpi Decoction for Senile Patients with Community-Acquired Pneumonia of Dificiency of Spleen Qi and Phlegm-Heat Obstructing the Lung Type
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    摘要:

    目的:观察揿针联合清肺健脾汤治疗脾气亏虚兼痰热壅肺型老年社区获得性肺炎(CAP) 的临床 疗效。方法:选取脾气亏虚兼痰热壅肺型老年CAP患者100例,按随机数字表法分为治疗组与对照组各50例。 2组均接受抗感染、化痰、止咳、退热、营养支持等西医常规治疗;治疗组加用揿针联合清肺健脾汤治疗。比 较2 组临床疗效,以及治疗前后降钙素原(PCT)、C-反应蛋白(CRP)、T 淋巴细胞亚群(CD3+、CD4+、 CD8+)、血清胃泌素水平变化。结果:治疗后,治疗组总有效率为98.00%,对照组为86.00%,组间比较,差异 有统计学意义(P<0.05)。治疗后,2组PCT、CRP水平均治疗前降低(P<0.05),且治疗组PCT、CRP水平低 于对照组(P<0.05)。治疗后,2组CD3+、CD4+水平较治疗前提高(P<0.05),CD8+水平较治疗前降低(P< 0.05);且治疗组CD3+、CD4+水平高于对照组(P<0.05),CD8+水平低于对照组(P<0.05)。治疗后,2组胃泌 素水平较均治疗前降低(P<0.05),且治疗组胃泌素水平低于对照组(P<0.05)。结论:揿针联合清肺健脾汤 治疗脾气亏虚兼痰热壅肺型老年CAP临床治疗效果显著,能有效下调炎症反应水平,提高机体免疫力,改善 肠胃功能。

    Abstract:

    Abstract: Objective: To observe the clinical effect of thumb-tack needling combined with Qingfei Jianpi Decoction on senile patients with community-acquired pneumonia (CAP) of dificiency of spleen qi and phlegm-heat obstructing the lung type. Methods:A total of 100 cases of senile patients with CAP of dificiency of spleen qi and phlegm-heat obstructing the lung type were divided into the treatment group and the control group according to the random number table method,with 50 cases in each group. Both groups received conventional western medical treatments such as anti-infection, expectorant, cough suppressant, fever reduction, and nutritional support, and the treatment group was additionally treated with thumb-tack needling combined with Qingfei Jianpi Decoction. The changes in the levels of procalcitonin (PCT), C-reactive protein (CRP), T lymphocyte subsets (CD3+ , CD4+ , CD8+ ) and serum gastrin before and after treatment and the clinical effects were compared between the two groups. Results: After treatment, the total effective rate was 98.00% in the treatment group and 86.00% in the control group,and the difference was significant (P<0.05). After treatment,the levels of PCT and CRP in the two groups were decreased when compared with those before treatment (P<0.05),and the levels of PCT and CRP in the treatment group were lower than those in the control group (P<0.05). After treatment, the levels of CD3+ and CD4+ in the two groups were decreased when compared with those before treatment (P<0.05), and CD8+ levels were increased when compared with those before treatment (P<0.05); the levels of CD3+ and CD4+ in the treatment group were lower than those in the control group (P<0.05),and CD8+ level was higher than that in the control group (P<0.05). After treatment, gastrin levels in the two groups were elevated when compared with those before treatment (P<0.05),and the gastrin level in the treatment group was higher than that in the control group (P<0.05). Conclusion: Thumb-tack needling combined with Qingfei Jianpi Decoction has a remarkable clinical effect on senile patients with CAP of dificiency of spleen qi and phlegm-heat obstructing the lung type,which can effectively down-regulate the levels of inflammatory responses,enhance the body immunity and improve the gastrointestinal function.

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袁晴丹,高羽迪,王琼,杨虎明.揿针联合清肺健脾汤治疗脾气亏虚兼痰热壅肺型老年社区获得性肺炎临床研究[J].新中医,2024,56(20):121-125

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  • 在线发布日期: 2024-10-29
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