Abstract： Objective： To observe the clinical effect of the combination use of Fuzheng Jiedu Prescription and Bifidobacterium Triple Viable Tablets on syndrome of spleen-stomach qi deficiency after surgery of gastric cancer，and its effects on intestinal microecology and nutritive indexes. Methods：A total of 90 cases of patients with syndrome of spleen-stomach qi deficiency after surgery of gastric cancer were selected and divided into the control group and the study group according to the random number table method， with 45 cases in each group. After postoperative food taking started， the control group was treated with Bifidobacterium Triple Viable Tablets， and the study group was treated with Fuzheng Jiedu Prescription based on the treatment of the control group. Both groups were treated for 14 days. The clinical effects，traditional Chinese medicine (TCM) syndrome scores，intestinal flora (Lactobacillus，Enterococcus faecalis， Bifidobacterium and Escherichia coli)， nutritive indexes (albumin and total protein) and incidence of complications were compared between the two groups. Results： After 14 days of treatment， the excellent rate of clinical effect in the study group was 75.56%， higher than that of 60.00% in the control group (P＜0.05). After 14 days of treatment， the scores of abdominal pain， bloating， nausea， poor appetite and digestion，mental fatigue and lack of strength，unformed stool and pale facial complexion in the two groups were lower than those five days after surgery (P＜0.05). The above seven TCM syndrome scores in the study group were lower than those in the control group (P ＜ 0.05). After 14 days of treatment， the numbers of Lactobacillus and Bifidobacterium in the two groups were increased when compared with those five days after surgery (P＜0.05)， and the number of Enterococcus faecalis and Escherichia coli were reduced when compared with those five days after surgery (P＜0.05). The numbers of Lactobacillus and Bifidobacterium in the study group were more than those in the control group (P＜0.05)， and the numbers of Enterococcus faecalis and Escherichia coli were less than those in the control group (P＜ 0.05). After 14 days of treatment，the levels of albumin and total protein in the two groups were higher than those five days after surgery (P＜0.05)，and the levels of albumin and total protein in the study group were higher than those in the control group (P＜0.05). During the treatment，the incidence of complications was 8.89% in the study group and 13.33% in the control group，there being no significance in the difference (P＞ 0.05). Conclusion： The combination use of Fuzheng Jiedu Prescription and Bifidobacterium Triple Viable Tablets can improve the intestinal microecology and nutritive indexes of patients with syndrome of spleenstomach qi deficiency after surgery of gastric cancer，and effectively relieve the clinical symptoms，and its curative effect is better than that of Bifidobacterium Triple Viable Tablets alone.