Abstract： Objective： To observe the clinical efficacy of Yiqi Tongbi Capsules combined with western medicine on stable angina pectoris (SAP) with qi deficiency and blood stasis syndrome. Methods：A total of 72 cases of SAP patients with qi deficiency and blood stasis syndrome were selected and divided into the treatment group and the control group according to the random number table method， with 36 cases in each group. Two cases from the treatment group and three cases from the control group were excluded， leaving 34 cases in the treatment group and 33 cases in the control group for the final study. The control group was treated with western medicine， and the treatment group was additionally given Yiqi Tongbi Capsules in addition to the treatment of the control group. Both groups were treated for four weeks. The efficacy of traditional Chinese medicine (TCM) syndromes and angina pectoris symptom， discontinue and reduction of Nitroglycerin，Seattle Angina Questionnaire (SAQ) scores，two-dimensional speckle tracking imaging (2D-STI) indexes， inflammation indexes， and blood lipid indexes were compared between the two groups. Results： The efficacy of TCM syndromes and angina pectoris symptom as well as the discontinue and reduction of Nitroglycerin in the treatment group were better than those in the control group (P＜0.05). After treatment，the scores of physical activity limitation (PL)，stable angina status (AS)，angina attack (AF)，treatment satisfaction (TS)，and disease perception (DP) in both groups were increased when compared with those before treatment (P＜0.05)； the scores of PL， AS， AF， and TS in the treatment group were higher than those in the control group (P＜0.05)； there was no significant difference in DP scores between the two groups (P＞0.05). After treatment， the values of global longitudinal strain (GLS) and global circumferential strain (GCS) in both groups were improved when compared with those before treatment (P＜0.05)，and the values of GLS and GCS in the treatment group were better than those in the control group (P＜0.05). After treatment， the levels of monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR)， hypersensitive C-reactive protein (hs-CRP)， and complement C1q tumor necrosis factor-related protein 1 (CTRP1) in both groups were reduced when compared with those before treatment (P＜0.05)，and the levels of MHR，hs-CRP，and CTRP1 in the treatment group were lower than those in the control group (P＜0.05). After treatment，the levels of total cholesterol (TC)，triglyceride (TG)，and lowdensity lipoprotein cholesterol (LDL-C) in both groups were decreased when compared with those before treatment (P＜0.05)， and the levels of HDL-C in both groups were elevated when compared with those before treatment (P＜0.05)；the levels of TC and LDL-C in the treatment group were lower than those in the control group (P＜0.05)， and the level of HDL-C in the treatment group was higher than that in the control group (P＜0.05)；there was no significant difference in TG levels between the two groups (P＞0.05). Conclusion：The combination of Yiqi Tongbi Capsules and western medicine in the treatment of SAP with qi deficiency and blood stasis syndrome can relieve the symptoms of angina pectoris，improve the quality of life，reduce the inflammatory responses，regulate the blood lipid levels，and promote the recovery of local ischemic myocardial blood supply，with good safety.