Abstract：Objective：To observe the clinical effects of lumbar abdominal combined manipulation in the treatment of mild degenerative lumbar spondylolisthesis (DLS) and its impact on spinal and pelvic parameters. Methods： A total of 120 patients with mild DLS were selected and divided into the control group， the observation group A， and the observation group B using the random number table method， with 40 patients in each group. The control group received fumigation and washing therapy with Ruanshang Waixi Prescription 1，the observation group A was treated with conventional massage therapy in addition to the control group， and the observation group B received lumbar abdominal combined manipulation in addition to the control group. All the three groups were treated for 14 days and followed up for one month. The clinical effects and spinal and pelvic parameters [thoracic kyphosis angle (TK)， lumbar lordosis angle (LL)， sagittal vertical axis (SVA)， pelvic incidence angle (PI)， pelvic tilt angle (PT)， and sacral slope (SS)] were compared among the three groups. Results：The total effective rate was 92.50% in the observation group B， 85.00% in the observation group A， and 77.50% in the control group， with significance in the difference (P＜0.05). After 14 days of treatment， TK and SS in all the three groups were increased when compared with those before treatment，and LL，SVA，PI，and PT were decreased when compared with those before treatment，with significance in differences (P＜0.05). After a one-month follow-up，TK and SS in all the three groups were increased when compared with those after 14 days of treatment，and LL， SVA，PI，and PT were declined when compared with those after 14 days of treatment，with significance in differences (P＜0.05). After 14 days of treatment and one month follow-up，TK and SS in the observation group B and the observation group A were higher than those in the control group at the same time，while LL， SVA， PI， and PT were lower than those in the control group at the same time； TK and SS in the observation group B were higher than those in the observation group A at the same time，while LL，SVA， PI，and PT in the observation group B were lower than those in the observation group A at the same time； the differences were significant (P＜0.05). Conclusion： The clinical effects of lumbar abdominal combined manipulation for mild DLS is definite， and it can effectively improve the spinal and pelvic parameters of patients.