Abstract：Objective：To observe the clinical effect of the combination use of modified Buyang Huanwu Decoction and acupuncture and low-frequency repetitive transcranial magnetic stimulation （rTMS） on post-stroke cognitive disorder. Methods：A total of 96 patients with post-stroke cognitive disorder treated in Hangzhou Shangcheng District People's Hospital from July 2022 to July 2023 were selected and divided into the control group and the observation group according to the random number table method，with 48 cases in each group. The control group was treated with rTMS， and the observation group was additionally treated with modified Buyang Huanwu Decoction combined with acupuncture based on the treatment of the control group. Both groups were treated for six weeks. The clinical effect， traditional Chinese medicine syndrome scores，cognitive function，hemorheology indexes and incidence of adverse reactions were compared between the two groups. Results： The total effective rate was 95.83% （46/48） in the observation group， higher than that of 81.25% （39/48） in the control group （P＜0.05）. After treatment，the traditional Chinese medicine syndrome scores in the two groups were dwindled when compared with those before treatment （P＜0.05），and the above scores in the observation group were lower than those in the control group （P＜0.05）. After treatment， the scores of Montreal Cognitive Assessment （MoCA） in the two groups were elevated when compared with those before treatment （P＜0.05）， and the MoCA score in the observation group was higher than that in the control group （P＜ 0.05）. After treatment，the levels of fibrinogen （Fib），plasma viscosity and hematocrit （HCT） in the two groups were down-regulated when compared with those before treatment （P＜0.05），and the above three levels in the observation group were lower than those in the control group （P＜0.05）. There was no significant difference being found in the comparison of the incidence of adverse reactions between the two groups （P ＞0.05）. Conclusion：The combination use of modified Buyang Huanwu Decoction and acupuncture and rTMS has a great curative effect on post-stroke cognitive disorder，which can improve the clinical symptoms，cognitive function and blood circulation with great safety.