Abstract: Objective: To observe the clinical effect of transcutaneous electrical acupoint stimulation combined with plantar pressure-based feedback training in the treatment of post-stroke hemiplegia and its effects on balance function and lower extremity surface electromyography signals. Methods: A total of 90 cases of patients with poststroke hemiplegia admitted to Wenzhou TCM Hospital of Zhejiang Chinese Medical University from January 2022 to January 2023 were divided into the control group and the trial group using a random number table method, with 45 patients in each group. Both groups took Aspirin Enteric-Coated Tablets. The control group received plantar pressure-based feedback training,and the trial group received transcutaneous electrical acupoint stimulation combined with plantar pressure-based feedback training. Both groups were treated for four weeks. After treatment, the clinical efficacy of the two groups was compared.Before and after treatment,the two groups were compared in terms of balance function [the Berg Balance Function Scale (BBS) and the Five Times Sit-to-Stand TEST (FTSST) ],lower extremity surface electromyography signals [root mean square (RMS) of surface electromyography signals of the tibialis anterior muscle, rectus femoris muscle, and gastrocnemius muscle on the affected side], and lower extremity motor function [Fugl-Meyer Assessment Scale- Lower Extremity (FMA-LE) ], walking ability (step size difference and walking speed), and activities of daily living [Functional Independence Measure (FIM) scores]. Results: After treatment, the total effective rate in the trial group was 93.02% (40/43),which was higher than the control group's 76.74% (33/ 43) . Both groups showed an increase in BBS scores compared to that before treatment,with the trial group having a higher BBS score than the control group (P<0.05) . The FTSST time in the two groups was shortened when compared with that before treatment, with the trial group having a shorter FTSST time than the control group (P<0.05) . The RMS of the tibialis anterior muscle,rectus femoris muscle,and gastrocnemius muscle on the affected sides in the two groups were increased when compared to those before treatment, and the RMS of the tibialis anterior muscle, rectus femoris muscle,and gastrocnemius muscle on the affected sides in the trial group were higher than those in the control group (P<0.05) . The FMA-LE and FIM scores in the two groups were increased when compared with those before treatment,and the FMA-LE and FIM scores in the trial group were higher than those in the control group (P<0.05) . The step difference in the two groups was shortened when compared with that before treatment, with the trial group having a shorter step difference than the control group (P<0.05) ; both groups showed an increase in walking speed compared to that before treatment,and the trial group had a higher walking speed than the control group (P<0.05) . Conclusion: Transcutaneous electrical acupoint stimulation combined with plantar pressure-based feedback training can effectively promote balance function and improve lower extremity surface electromyography signals,lower extremity motor function,and walking and daily activity abilities in the treatment of post-stroke hemiplegia.