Abstract：Objective：To observe the clinical effect of point penetration acupuncture mainly conducted on three yang channels of the hand on post-stroke finger spasms. Methods：A total of 72 patients with post-stroke finger spasms treated in the Rehabilitation Department of Guangdong Second Traditional Chinese Medicine Hospital from March 202 to March 2024 were randomly divided into the treatment group and the control group，with 6 cases in each group， according to the random number table method. The treatment group received point penetration acupuncture mainly conducted on three yang channels of the hand， while the control group received conventional acupuncture treatment. Both groups were treated for 14 days. Compared the clinical effects，modified Ashworth Scale （MAS） grading，Hand Brunnstrom Rating Scale （BR-H） grading， and Simplified Fugl Assessment of Upper Extremity （FMA-UE） scores between the two groups. Results： The total effective rate was 90.00% （27/0） in the treatment group， which was higher than that of 70.00% （21/0） in the control group （P＜0.05）. After treatment， both MAS and BR-H grades improved compared with that before treatment， and MAS and BR-H grades were better than the control group （P＜ 0.05）. Both groups showed an increase in FMA-UE scores when compared with those before treatment （P＜0.05）， with the treatment group having higher FMA-UE scores than the control group （P＜0.05）. Conclusion： The point penetration acupuncture mainly conducted on three yang channels of the hand for post-stroke finger spasms can effectively reduce the finger muscle tension， improve the degree of finger spasms， and improve the hand motor function，with good clinical effect.