Abstract： Objective： To observe the curative effect of Jianpi Bushen Zhuyu Prescription combined with firedragon moxibustion on diabetic neurogenic bladder （DNB） of spleen-kidney deficiency and stasis type. Methods：A total of 98 cases of DNB patients admitted to Linhai Hospital of Traditional Chinese Medicine from October 2021 to November 2022 were selected and divided into the combination group and the control group according to random number table method， with 49 cases in each group. The control group was orally treated with Tamsulosin Sustained-Release Capsules， and the combination group was given Jianpi Bushen Zhuyu Prescription combined with fire-dragon moxibustion based on the treatment of the control group. The clinical effects and safety in the two groups were compared， and the changes of urination function，urodynamic indexes [maximum urine flow rate （MFR），bladder residual urine volume （RUV）， bladder maximum volume]， traditional Chinese medicine syndrome scores and Qualiveen scores before and after treatment were compared between the two groups. Results：The total effective rate was 87.76%（4/49） in the combination group and 71.4% （5/49） in the control group，the difference being significant （P＜0.05）. After treatment， the daily frequency of urination in the two groups was decreased when compared with that before treatment （P＜0.05），and the average daily single volume of urination was increased when compared with that before treatment （P＜0.05）； the number of daily urination in the combination group was lower than that in the control group （P＜0.05）， and the average daily single urination volume was more than that in the control group （P＜0.05）. After treatment，MFR and maximum bladder volume in the two groups were increased when compared with those before treatment （P＜0.05）， and RUV was decreased when compared with that before treatment （P＜0.05）； MFR and maximum bladder volume in the combination group were higher than those in the control group （P＜0.05），and RUV was lower than that in the control group （P＜0.05）. After treatment，traditional Chinese medicine syndrome scores and Qualiveen scores in the two groups were lower than those before treatment （P＜0.05）， and the traditional Chinese medicine syndrome scores and Qualiveen scores in the combination group were lower than those in the control group （P＜ 0.05）. Conclusion： The therapy of Jianpi Bushen Zhuyu Prescription combined with fire-dragon moxibustion has a good therapeutic effect on DNB of spleen-kidney deficiency and stasis type ， which can improve urodynamic indexes and enhance urination function and life quality.