School of Guangdong University of Chinese Medicine，Dongguan Guangdong 523000，China Abstract： Objective： To explore the medication rules of Professor YE Xiaohan in treating chronic pulmonary heart disease with Chinese medicinals. Methods：The cases where Professor YE used Chinese medicine to treat chronic pulmonary heart disease from July 2018 to June 2023 were collected and screened one by one to obtain Professor YE's prescriptions for chronic pulmonary heart disease. The prescriptions were entered into the Traditional Chinese Medicine Inheritance Assistant Platform V2.5， and given data mining methods such as frequency analysis， association rule analysis， and entropy hierarchical clustering analysis for the use frequency of Chinese medicinals and the association rules among Chinese medicinals， core combinations， and new prescription combinations. Results ： A total of 343 prescriptions were obtained， involving 3 593 Chinese medicinals. The top 10 in use frequency from high to low were Glycyrrhizae Radix et Rhizoma， Poria， Astragali Radix， Salviae miltiorrhizae Radix et Rhizoma， Pinelliae Rhizoma， Atractylodis Macrocephala Rhizoma， Descurainiae Semen Lepidii Semen， Armeniacae Semen Amarum， Schisandrae Chinensis Pructus and Cinnamomi Ramulus. Highly-used Chinese medicinals （frequency ≥ 40 times， except Glycyrrhizae Radix et Rhizoma） were analyzed by association rules，and the support degree was ≥ 0.12，and 29 medicinal pairs were obtained， including Atractylodis Macrocephala Rhizoma-Poria， Pinelliae Rhizoma-Poria， etc. With a confidence of ≥ 0.60， a total of 18 medicinal combinations were worked out， including “Atractylodis Macrocephala Rhizoma， Cinnamomi Ramulus→Poria”，“Atractylodis Macrocephala Rhizoma， Aconiti Lateralis Radix Praeparata→Poria” and others. The entropy hierarchy analysis suggested 8 core medicinal combinations and 4 new prescriptions. Conclusion：Professor YE in treating chronic pulmonary heart disease is mainly to fortify the spleen and tonify the kidney，boost qi and warm yang，resolve phlegm and induce diuresis，activate blood and move qi，and resolve stasis. At the same time， it is supplemented by tonifying yin， clearing heat and calming panting. Various treatment methods are often used in combination with each other.