Abstract：Objective：To observe the therapeutic effect of Chinese medicine aromatherapy on pernicious vomiting during pregnancy of deficiency of spleen-stomach type. Methods： A total of 148 patients with pernicious vomiting during pregnancy of deficiency of spleen-stomach type admitted to the Affiliated Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Chinese Medical University from January 202 to December 202 were randomly divided into an observation group and a control group，with 74 cases in each group. Both groups were given conventional treatment for pernicious vomiting during pregnancy. The observation group wore Chinese medicine aromatic wristbands on this basis to implement Chinese medicine aromatherapy， while the control group wore ordinary cloth wristbands. The two groups were treated continuously for five days. Clinical effects were compared between the two groups. The changes in traditional Chinese medicine symptom scores，scores of the Pregnancy Unique Quantification of nausea and vomiting，serum motilin，conversion rates of urine ketone body，and levels of serum β-human chorionic gonadotropin （β-HCG） were compared between the two groups before and after treatment. Results：The total effective rate of clinical efficacy in the observation group was 86.49% （64/74），while the total effective rate of clinical efficacy in the control group was 59.46% （44/74）， with the difference being significant （P＜0.05）. After treatment， the traditional Chinese medicine symptom scores in the two groups were decreased when compared with those before treatment （P＜0.05）， and the scores in the observation group were lower than those in the control group （P＜0.05）. After treatment，both groups showed a decrease in PUQE scores when compared with those before treatment （P＜0.05）， with the observation group having a lower PUQE score than the control group （P＜0.05）. After treatment，both groups showed an increase in serum motilin levels when compared with those before treatment （P＜0.05），with the observation group having higher serum motilin levels than the control group （P＜0.05）. After treatment，the conversion rate of urine ketone body in the observation group was 8.78% （62/74），higher than that of 60.81% （45/74） in the control group， with the difference being significant （P＜0.05）. After treatment， the serum levels of β-HCG in the two groups were increased when compared with those before treatment （P＜0.05），but there was no significant difference between the two groups （P＞0.05）. Conclusion：Chinese medicine aromatherapy has a good therapeutic effect on the treatment of pernicious vomiting during pregnancy of deficiency of spleen-stomach type，which helps to alleviate the symptoms and improve the negative conversion rate of urinary ketone body.