Abstract Objective： To analyze the medication law of traditional Chinese medicine （TCM） in treating acute myocardial infarction by using the Ancient and Modern Medical Record Cloud Platform. Methods：The literature on the treatment of acute myocardial infarction with TCM published in China National Knowledge Infrustructure， WanFang Data Knowledge Service Platform，China Science and Technology Journal Database，PubMed，Embase，and Web of Science databases was searched. Extract TCM prescription data. The data mining module of the Ancient and Modern Medical Record Cloud Platform was used to conduct drug frequency statistics，attribute（ four qi，five flavors，meridian tropism，efficacy） analysis，association rule analysis，cluster analysis and complex network analysis. Results：①A total of 194 Chinese medicine prescriptions were retrieved， involving 191 Chinese medicines， with a cumulative frequency of 1 745 times. There are 20 Chinese medicines that are used more than 20 times， and the top 5 Chinese medicines are Salviae Miltiorrhizae Radix et Rhizoma，Astragali Radix，chuanxiong Rhizoma，Paeoniae Radix Rubra and Angelicae sinensis Radix. ② Analysis results of attributes of Chinese medicine. Four Qi：mainly warm，followed by slightly cold，neutral，cold and slightly warm. Five flavors：mainly sweet，followed by pungent，bitter，slightly bitter and sour. Meridian tropism： mainly liver， followed by heart， lung， spleen and stomach. Drug efficacy： it mainly promotes blood circulation and removes blood stasis， followed by promoting fluid circulation and nourishing blood， dredging menstruation and relieving pain， cooling blood and eliminating carbuncle， clearing the heart and relieving troubles. ③ Analysis results of association rules. According to the degree of support from high to low，the top 5 medicine pairs are Astragali Radix-Salviae Miltiorrhizae Radix et Rhizoma，Chuanxiong Rhizoma-Salviae Miltiorrhizae Radix et Rhizoma， Paeoniae Radix Rubra-Salviae Miltiorrhizae Radix et Rhizoma， Angelicae Sinensis Radix-Chuanxiong Rhizoma， and Paeoniae Radix Rubra-Chuanxiong Rhizoma. ④Results of cluster analysis. A total of 3 clusters were obtained. Category 1： Salviae Miltiorrhizae Radix et Rhizoma， Astragali Radix， Chuanxiong Rhizoma； Category 2： Ophiopogonis Radix， Notogyri Radix， Ginseng Radix et Rhizoma， Trichosanthis Fructus， Glycyrrhizae Radix et Rhizoma Praeparata cum Melle， Cinnamomi Ramulus； Category 3： Angelicae Sinensis Radix， Carthami Flos， Persicae Semen， Paeoniae Radix Rubra， Codonopsis Radix， Glycyrrhizae Radix et Rhizoma. ⑤Results of complex network analysis. It is concluded that the core prescription medicine composition is Astragali Radix， Salviae Miltiorrhizae Radix et Rhizoma， Chuanxiong Rhizoma， Paeoniae Radix Rubra， Angelicae Sinensis Radix， Codonopsis Radix， Carthami Flos， Ophiopogonis Radix， Notogyri Radix， Glycyrrhizae Radix et Rhizoma. The core prescription is modified Buyang Huanwu Decoction. Conclusion： Chinese medicine treatment of acute myocardial infarction is mainly based on promoting blood circulation and removing blood stasis， tonifying qi and invigorating spleen，supplemented by promoting qi，cooling blood，nourishing yin and promoting fluid production. The medication should be sweet in flavor and warm in nature，mainly returning to the liver meridian，and the clinical symptoms should be coordinated with qi and blood， taking into account both of the symptoms and root cause， integrating five internal organs， analysising the pathogensis and differentiating syndromes. TCM intervention should be used in the whole process of acute myocardial infarction treatment to improve the prognosis of acute myocardial infarction， reduce complications and enhance the level and intensity of intervention by TCM.