基于数据挖掘技术分析《王孟英医学全书》中痰证与脉象、用药的关联性
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R249

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大学生创新创业训练计划项目(202310572140)


Correlation Analysis of Phlegm Syndrome, Pulse Manifestation, and Medication in Wang Meng Ying Yi Xue Quan Shu Using Data Mining Techniques
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    摘要:

    目的:从《王孟英医学全书》的医案中研究痰证与脉象、用药之间的关联性,归纳总结王孟英诊 治痰证的特点。方法:从《王孟英医学全书》中筛选符合标准的医案,对纳入医案的诊次进行编号,提取医案 中的脉象、证候、用药等信息。通过Microsoft Excel 2021软件建立数据库,对数据进行频次分析。应用SPSS Modeler 18软件中的Apriori算法,对纳入医案的脉象-证候、用药-证候和痰证医案的脉象-用药、用药-脉象进 行关联规则分析。结果:共纳入医案444例,共计503诊次,其中有关痰证的医案151例,166诊次,共出现 21种脉象。频次≥30次的脉象分别为滑脉、弦脉、数脉、软脉(濡脉),其中滑脉和弦脉的频次均为102次, 频率均为61.4%(102/166);其次是数脉、软脉(濡脉)。左、右手脉象中,滑脉的诊次以右滑脉为主,弦脉的 诊次以左弦脉为主,数脉的诊次以左数脉为主。共检索出169种与痰证有关的中药,频次>30次的中药有 15 种,化痰止咳平喘药有7种,清热药有5种,开窍药有1种,补虚药有2种。痰证与缓脉、浮脉、溢脉、滑 脉等脉象关联性较强,与薤白、竹沥、苦杏仁等中药的关联性较强。151例痰证医案中,滑脉主要与清热药、 化痰药、利水渗湿药有关,弦脉与清热药、补虚药、化痰药有关,数脉与清热药、补虚药有关;竹茹、旋覆 花、天花粉等药物与溢脉等脉象关联性强。结论:王孟英诊断痰证的脉象主要为滑脉、缓脉、浮脉、溢脉,治 疗时多使用竹茹清肺化痰,薤白、半夏、苦杏仁治疗寒痰结胸,黄连、栀子配伍治疗痰热扰心,鲜海蜇、鲜荸 荠清痰热与肝经之热,知母、天花粉清痰热、顾护阴液。王孟英治疗痰证的脉、药、证关联思路清晰,凭脉诊 随证施治,其处方用药规律对现代痰证的诊治仍具重要的临床参考价值和指导意义。

    Abstract:

    Abstract:Objective:To study the correlation among phlegm syndrome,pulse manifestation,and medication in the medical cases from Wang Meng Ying Yi Xue Quan Shu (Wang Mengying's Case Records), and to summarize WANG Mengying's diagnostic and treatment characteristics for phlegm syndrome. Methods: Standard-compliant medical cases were screened from Wang Meng Ying Yi Xue Quan Shu, and the visits of included medical cases were numbered. Information such as pulse manifestations, syndromes, and medication was extracted. A database was established using Microsoft Excel 2021 software for frequency analysis of the data. The Apriori algorithm in SPSS Modeler 18 software was applied to perform association rule analysis on pulse manifestation-syndrome and medicationsyndrome pairs in the included medical cases, as well as pulse manifestation-medication and medication-pulse manifestation pairs in the medical cases related to phlegm syndrome. Results:A total of 444 medical cases,involving 503 visits, were included, with 151 cases (166 visits) related to phlegm syndrome, showing 21 types of pulse manifestations. The pulse manifestations with a frequency ≥30 were slippery pulse,wiry pulse,rapid pulse,and soft pulse (soggy pulse), among which slippery pulse and wiry pulse had the highest frequency of 102 (61.4%, 102/ 166), followed by rapid pulse and soft pulse (soggy pulse) . Among the pulse manifestations on the left and right hands,the majority of slippery pulse diagnoses were on the right hand,wiry pulse on the left hand,and rapid pulse on the left hand. A total of 169 Chinese medicinals related to phlegm syndrome were retrieved,with 15 medicinals having a frequency over 30; among them, there were 7 medicinals for dissolving phlegm and relieving cough and panting, 5 heat-clearing medicinals,1 resuscitate medicinals,and 2 supplementing medicinals. There was a strong correlation between phlegm syndrome and moderate pulse, floating pulse, overflow pulse, and slippery pulse, as well as with Chinese medicinals such as Allii Macrostemonis Bulbus,Bambusa Textilis Extract,and Armeniacae Semen Amarum. In the 151 medical cases of phlegm syndrome, slippery pulse was mainly associated with heat-clearing medicinals, phlegm-resolving medicinals, and urination-promoting and dampness percolating medicinals; wiry pulse was associated with heat-clearing medicinals, supplementing medicinals, and phlegm-resolving medicinals; and rapid pulse was associated with heat-clearing medicinals and supplementing medicinals. Medicinals such as Bambusae Caulis in Taeniam, Inulae Flos, and Trichosanthis Radix were strongly associated with overflow pulse and other pulse manifestations. Conclusion:WANG Mengying mainly diagnosed phlegm syndrome based on slippery pulse,moderate pulse,floating pulse,and overflow pulse. In treatment,he frequently used Bambusae Caulis in Taenias to clear lung heat and resolve phlegm, Allii Macrostemonis Bulbus, Pinelliae Rhizoma, and Armeniacae Semen Amarum to treat cold-phlegm accumulation in the chest,the combination of Coptidis Rhizoma and Gardeniae Fructus to treat phlegmheat disturbing the heart, fresh jellyfish and fresh Eleocharis tuberosa to clear phlegm-heat and liver meridian heat, and Anemarrhenae Rhizoma and Trichosanthis Radix to clear phlegm-heat and nourish yin fluid. WANG Mengying's diagnostic and treatment approach of pulse, medicinals, and syndrome for phlegm syndrome was clear, relying on pulse diagnosis and treating according to syndromes. His prescription and medication patterns still have important clinical reference value and guiding significance for the modern diagnosis and treatment of phlegm syndrome.

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余佳蓓,林国栋,杨晓华,林沐萱,黄幸怡,陈紫桐,唐永祥.基于数据挖掘技术分析《王孟英医学全书》中痰证与脉象、用药的关联性[J].新中医,2025,57(5):47-54

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  • 在线发布日期: 2025-03-17
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