八段锦联合升阳贴对慢性心力衰竭患者心功能、中医证候及血清学指标的影响
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R259

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四川省中医药管理局中医药科研专项课题(2023MS060);西南医科大学中西医结合专项(2024ZXYZX39);西南医科大学项 目(2024ZKY073)


Effect of Combination Use of Eight Pieces of Brocade and Shengyang Plaster on Heart Function,Traditional Chinese Medicine Syndromes and Orrhology Indexes of Patients with Chronic Heart Failure
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    摘要:

    目的:观察八段锦联合升阳贴干预慢性心力衰竭的疗效。方法:选取2022年6月—2023年6月西 南医科大学附属中医医院收治的108例慢性心力衰竭患者,按随机数字表法分为对照组及观察组各54例。对照 组在常规治疗基础上予以穴位敷贴,观察组在对照组基础上联合八段锦干预。比较2组临床疗效及不良反应发 生情况,比较2组干预前后NYHA 心功能分级、中医证候积分、左室射血分数(LVEF)、每搏出量(SV)、 N 末端脑钠肽前体(NT-ProBNP) 的变化。结果:干预后,2组心功能分级均得到优化,观察组心功能分级优 于对照组(P<0.05)。干预后,2组中医症状评分均较治疗前下降(P<0.05),观察组中医症状评分低于对照 组(P<0.05)。干预后,2 组NT-ProBNP 水平均较干预前下降(P<0.05),LVEF、SV 水平均较干预前上 升(P<0.05);观察组NT-ProBNP水平均低于对照组(P<0.05),LVEF、SV水平高于对照组(P<0.05)。对 照组临床疗效总有效率为70.37% (38/54),观察组临床疗效总有效率为88.89% (48/54),2组临床疗效比较, 差异有统计学意义(P<0.05)。治疗过程中,2组均未出现严重不良反应。结论:八段锦联合升阳贴可有效改 善慢性心力衰竭患者心功能,改善血流动力学,缓解心衰症状,提升患者生活质量,康复效果良好。

    Abstract:

    Abstract: Objective: To observe the curative effect of the combination use of eight pieces of brocade and Shengyang Plaster on chronic heart failure. Methods:A total of 108 patients with chronic heart failure admitted into the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University were selected from June 2022 to June 2023 and divided into the control group and the observation group according to the random number table method,with 54 cases in each group. The control group was given acupoints application based on the routine treatment, and the observation group was additionally given the intervention of eight pieces of brocade based on the treatment of the control group. The clinical effects and the incidence of adverse reactions,and the changes of NYHA functional classification of heart failure, traditional Chinese medicine syndrome scores, left ventricular ejection fraction (LVEF), stroke volume (SV) and N-terminal pro B-type natriuretic peptide (NT-ProBNP) before and after intervention were compared between the two groups. Results:After intervention,the functional classification in the two groups was improved,and the functional classification in the observation group was better than that in the control group (P<0.05). After intervention, the traditional Chinese medicine syndrome scores in the two groups were reduced when compared with those before treatment (P<0.05),and the above scores in the observation group were lower than those in the control group (P<0.05). After intervention, the levels of NT-ProBNP in the two groups were dwindled when compared with those before intervention (P<0.05), and the LVEF and SV levels were elevated when compared with those before intervention (P<0.05); the level of NT-ProBNP in the observation group was lower than those in the control group (P<0.05),and the LVEF and SV level were higher than that in the control group (P<0.05). The total effective rate was 70.37% (38/54) in the control group and 88.89%(48/54) in the observation group, the difference being significant (P<0.05). During the treatment, no serious adverse reactions occurred in the two groups. Conclusion: The combination use of eight pieces of brocade and Shengyang Plaster can effectively improve the heart function and hemodynamics of patients with chronic heart failure,relieve the symptoms of heart failure and enhance the quality of life with great rehabilitation effect.

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武晋雯,薛进宜,黄静雯,赵淑飞,杨雪.八段锦联合升阳贴对慢性心力衰竭患者心功能、中医证候及血清学指标的影响[J].新中医,2025,57(5):55-59

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  • 在线发布日期: 2025-03-17
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