Abstract: Objective: To explore the acupoint selection rules for acupoint stimulation therapy of slow transit constipation (STC) based on data mining. Methods: Clinical research literature on acupoint stimulation therapy for STC was retrieved from China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform (Wanfang), China Science and Technology Journal Database (VIP), China Biomedical Literature Database (SinoMed), Web of Science, PubMed, and Embase databases from the establishment of the databases to May 27,2024. A database was established by using Microsoft Excel software;association rule analysis and clustering analysis were performed on acupoints using R4.4.0 software; Gephi0.10.0 software was used for complex network analysis. Results : A total of 144 articles were included, and 195 core prescriptions were extracted, involving 64 acupoints with a cumulative frequency of 1 036 times. The top five acupoints with the highest frequency of use are Tianshu (ST5) point, Zusanli (ST36) point, Dachangshu (BL25) point, Shangjuxu (ST37) point, and Zhigou (TE6) point. The acupoints mainly belong to the foot yangming stomach meridian,conception vessel,and the foot taiyang bladder meridian,with a higher proportion of acupoints in the chest,abdomen,and lower limbs;frontmu point is the most commonly used specific acupoint; acupuncture is a commonly used intervention measure. Association rule analysis showed that the core acupoint combination is Zusanli (ST36) point- Tianshu (ST5) point- Shangjuxu (ST37) point- Guanyuan (RN4) point;cluster analysis resulted in five effective clusters,and the analysis of tonifying and purging acupoints showed that the main operative techniques used in the treatment process were supplementing method and even supplementation and drainage method. Conclusion:The acupuncture sites for treating STC are mostly selected in the chest and abdomen, with a focus on the front-mu point. The foot yangming stomach meridian, conception vessel, and the foot taiyang bladder meridian are often selected, with Tianshu (ST5) point, Zusanli( ST36) point,Shangjuxu( ST37) point,and Dachangshu( BL25) point as the core acupoints.