Abstract：Insomnia is believed to be related to the dysfunction of the shaoyang pivot and the imbalance of yin and yang in Chinese medicine. The treatment principle involves harmonizing the shaoyang and balancing yin and yang， which can be achieved using formulas containing Bupleuri Radix. Chaihu and Longgu Muli Decoction can harmonize the shaoyang， tranquilize the heart， and calm the mind， making it particularly suitable for treating insomnia. It can be modified according to the patient's accompanied symptoms， which helps to expand the clinical application of oral administration of Chinese medicine in treating insomnia.